卵巢正常大小癌综合征^(18)F-FDGPET-CT表现  

^(18)F-FDGPET-CT findings in normal-sized ovary carcinoma syndrome

作　　者：文政芳[1] 岳军燕 谢文秀 赵淑珍[1] 尹山兰[1] 郭喆 WEN Zhengfang;YUE Junyan;XIE Wenxiu;ZHAO Shuzhen;YIN Shanlan;GUO Zhe(Department of Obstetrics and Gynecology,the First Affiliated Hospital of Xinxiang Medical University,Xinxiang 453100,China;Department of Radiology,the First Affiliated Hospital of Xinxiang Medical University,Xinxiang 453100,China;Department of Nuclear Medicine,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210000,China)

机构地区：[1]新乡医学院第一附属医院妇产科,河南新乡453100 [2]新乡医学院第一附属医院放射科,河南新乡453100 [3]南京医科大学第一附属医院核医学科,江苏南京210000

出　　处：《中国医学物理学杂志》2021年第5期587-591,共5页Chinese Journal of Medical Physics

基　　金：河南省科技厅科技攻关项目(182102310494)。

摘　　要：目的:探讨18氟-氟代脱氧葡萄糖(^(18)F-FDG)正电子发射断层扫描(PET-CT)显像在卵巢正常大小癌综合征(NOCS)原发病灶确定、全身情况评估等方面的应用价值。方法:对6例行全身PET-CT检查并最终根据临床及病理结果确诊为NOCS患者的PET-CT影像资料进行回顾性分析。结果:6例患者中3例最终病理为卵巢浆液性乳头状癌,1例为卵巢外腹膜浆液性乳头状腺癌,1例为结肠癌转移,1例为非卵巢来源原因不明的转移性腺癌。^(18)F-FDGPET-CT诊断卵巢癌2例,这2例患者PET-CT影像因腹腔积液的映衬卵巢CT影像清晰,并可见卵巢部位放射性摄取增高;PET-CT诊断卵巢外腹膜浆液性乳头状腺癌1例;1例PET-CT假阴性最终被确诊为卵巢癌;1例PET-CT未发现原发灶的患者最后诊断为肠道来源肿瘤。结论:^(18)F-FDGPET-CT对于查找NOCS原发灶有一定的应用价值,卵巢浆液性乳头状癌是本文6例患者的主要组成部分,肿瘤标志物有一定提示意义。Objective To investigate the application value of ^(18)F-fluorodeoxyglucose positron emission tomography-computed tomography(^(18)F-FDGPET-CT)in detecting the primary lesion of normal-sized ovary carcinoma syndrome(NOCS)and assessing the general condition of patients.Methods The imaging data of 6 clinically-and pathologically-confirmed NOCS patients who underwent PET-CT examination were analyzed retrospectively.Results Three of the 6 cases were pathologically dignosed with ovarian papillary serous carcinoma,1 with extraovarian peritoneal serous papillary carcinoma(EPSPC),1 with intestinal tumor metastased from colon cancer,and the remaining 1 case with nonovarian adnocarcinoma with unknown origin.The PET-CT images of 2 cases of ovarian cancer diagnosed by ^(18)F-FDGPET-CT showed massive ascites and well displayed ovaries against the massive ascites,and an increasing radioactivity uptake at ovarian was also demonstrated.There were 1 case of EPSPC diagnosed by PET-CT,1 case of false-negative PET-CT findings which was finally confirmed as ovarian cancer;and the case in which the original lesion was unknown was finally diagnosed with tumor originating from the intestine.Conclusion ^(18)F-FDGPET-CT has certain value in detecting the original lesion of NOCS.Ovarian papillary serous carcinoma is the main component of the 6 NOCS cases,and tumor markers can be indicators in NOCS.

关 键 词：卵巢正常大小癌综合征 18氟-氟代脱氧葡萄糖 正电子发射断层扫描 卵巢浆液性乳头状癌 卵巢外腹膜浆液性乳头状腺癌 

分 类 号：R816.91[医药卫生—放射医学]