队列研究在针灸临床研究中的应用与思考  

Application and thinking of cohort study in clinical research of acupuncture and moxibustion

作　　者：郝瑞民 樊小农[1,2,3,4,5] 李礼 沈燕[1,2,3,4,5] 刘健 马延宁[2] 王舒 HAO Rui-min;FAN Xiao-nong;LI Li;SHEN Yan;LIU Jian;MA Yan-ning;WANG Shu(Institute of Acupuncture and Moxibustion,First Teaching Hospital of Tianjin University of TCM,Tianjin 300193,China;First Teaching Hospital of Tianjin University of TCM,Tianjin 300193;Tianjin Key Laboratory of Acupuncture and Moxibustion Sciences,Tianjin 300193;Key Laboratory of Acupuncture Encephalopathy,State Administration of Traditional Chinese Medicine,Tianjin 300193;National Clinical Research Center for Acupuncture and Moxibustion of Chinese Medicine,Tianjin 300193)

机构地区：[1]天津中医药大学第一附属医院针灸研究所,天津300193 [2]天津中医药大学第一附属医院,天津300193 [3]天津市针灸学重点实验室,天津300193 [4]国家中医药管理局脑病针刺疗法重点研究室,天津300193 [5]国家中医针灸临床医学研究中心,天津300193

出　　处：《中国针灸》2021年第5期545-548,共4页Chinese Acupuncture & Moxibustion

基　　金：国家重点研发计划资助项目:2018YFC1705004;天津市科技计划项目创新平台专项:18PTLCSY00040。

摘　　要：队列研究在国内中医药临床研究中得到重视和广泛应用,但在针灸领域应用较少。本文介绍队列研究的发展背景、基本概念、优势以及局限,分析当前针灸疗效评价存在的问题以及队列研究在针灸领域的应用现状,探讨这一方法在针灸临床研究中的可行性与应用价值,并提出了严谨设计、控制选择性偏倚、控制队列迁移和降低失访的方法学建议,旨在为针灸临床研究拓宽新的思路和方法。Cohort study has been greatly considered and widely used in clinical research of traditional Chinese medicine in China,but it is seldom applied in the field of acupuncture and moxibustion.This paper introduces the development background,basic concepts,advantages and limitations of cohort study,analyzes the existing problems in the evaluation of acupuncture and moxibustion curative effect and development status of cohort study in the cycle of acupuncture and moxibustion,explores the feasibility and value of such method in clinical research of acupuncture and moxibustion and proposes the methodological suggestions on rigorous design,control of selective bias,control of cohort migration and reduction of loss to follow-up,aiming at broadening the new ideas and methods for clinical research of acupuncture and moxibustion.

关 键 词：队列研究 针灸 临床研究 循证医学 

分 类 号：R245[医药卫生—针灸推拿学]