Iron Catalyzed Isomerization of a-Alkyl Styrenes to Access Trisubstituted Alkenes  

作　　者：Songgen Xu Guixia Liu Zheng Huang 

机构地区：[1]State Key Laboratory of Organometallic Chemistry,Center for Excellence in Molecular Synthesis,Shanghai Institute of Organic Chemistry,University of Chinese Academy of Sciences,Chinese Academy of Sciences,345 Lingling Road,Shanghai 200032,China [2]Chang-Kung Chuang Institute,East China Normal University,Shanghai 200062,China [3]School of Chemistry and Material Sciences,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,1 Sub-lane Xiangshan,Hangzhou,Zhejiang 310024,China

出　　处：《Chinese Journal of Chemistry》2021年第3期585-589,共5页中国化学（英文版）

基　　金：the National Natural Science Foundation of China(Nos.21825109,21821002,21732006);the National Basic Research Program of China(No.2016YFA0202900);the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB20000000);the Chinese Academy of Sciences Key Research Program of Frontier Sciences(No.QYZDB-SSW-SLH016);the K.C.Wong Education Foundation,and the Science and Technology Commission of Shanghai Municipality(No.17JC1401200)is gratefully acknowledged.

摘　　要：Main observation and conclusion Stereoselective isomerization of a-alkyl styrenes is accomplished using a new iron catalyst supported by phosphine-pyridine-oxazoline(PPO)ligand.The protocol provides an atom-efficient and operationally simple approach to trisubstituted alkenes in high yields with excellent regio-and stereoselectivities under mild conditions.The results of deuterium-labelling and radical trap experiments are consistent with an iron-hydride pathway involving reversible alkene insertion andβ-H elimination.

关 键 词：CATALYSIS IRON lsomerization Trisubstituted alkenes STEREOSELECTIVITY 

分 类 号：O62[理学—有机化学]