肠道菌群与骨骼肌消耗症的研究进展  

Research progress on intestinal flora and skeletal muscle consumption

作　　者：赵俊花 牛洁(综述) 周萍(审校)[1] ZHAO Junhua;NIU Jie;ZHOU Ping(Department of pediatrics,Pediatrics of the Second Affiliated Hospital of Harbin Medical University,Harbin 150086)

机构地区：[1]哈尔滨医科大学附属第二医院儿科,哈尔滨150086

出　　处：《肾脏病与透析肾移植杂志》2021年第2期175-179,共5页Chinese Journal of Nephrology,Dialysis & Transplantation

基　　金：哈尔滨医科大学附属第二医院中青年创新科学研究基金(CX2016-03);教育部“春晖计划”合作科研项目(HLJ2019023)。

摘　　要：骨骼肌在人体日常活动中发挥重要作用.肿瘤、慢性肾脏病及营养不良等疾病时,由于骨骼肌能量消耗过多,患者最终表现为骨骼肌萎缩.对"肠-肌"轴的研究表明,肠道菌群通过多种途径参与骨骼肌消耗,影响骨骼肌萎缩.肠道菌群与骨骼肌消耗之间的关系,使得通过干预肠道菌群来预防和治疗骨骼肌萎缩成为可能.Skeletal muscle plays an important role in daily activities of human body.In the state of cancer,chronic kidney disease and malnutrition,due to excessive energy consumption of skeletal muscle,patients eventually show skeletal muscle atrophy.Studies on“gut-muscle”axis have shown that intestinal microflora participate in skeletal muscle consumption and affect skeletal muscle atrophy through various channels.The relationship between intestinal flora and skeletal muscle consumption makes it possible to prevent and treat skeletal muscle atrophy by interventing intestinal flora.

关 键 词：肠道菌群 骨骼肌萎缩 益生菌 

分 类 号：R685[医药卫生—骨科学]