清热理血汤对湿热瘀结型盆腔炎性疾病后遗症患者疗效及炎性因子、血液流变学指标的影响  

Efficacy of Qingre Lixue Decoction(清热理血汤)on Patients with Sequelae of Pelvic Inflammatory Disease and Its Influence on Inflammatory Factors and Hemorheological Indexes

作　　者：齐金羚 王巍[2] QI Jinling;WANG Wei(Shenyang Maternity and Child Health Hospital,Shenyang 110032,Liaoning,China;Kunming Medical University,Kunming 650001,Yunnan,China)

机构地区：[1]沈阳市妇幼保健院,辽宁沈阳110032 [2]昆明医科大学,云南昆明650001

出　　处：《辽宁中医药大学学报》2021年第3期187-190,共4页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：目的探究与分析清热理血汤对湿热瘀结型盆腔炎性疾病后遗症患者的疗效及炎性因子、血液流变学指标的影响。方法选取我院自2018年3月—2020年3月收治的82例湿热瘀结型盆腔炎性疾病后遗症患者,采取随机数字表法分为对照组与观察组,每组各41例,对照组给予康妇炎胶囊治疗,观察组在对照组基础上加用清热理血汤治疗,对比两组临床疗效、中医证候积分、炎性因子及血液流变学指标变化、性生活质量评价。结果观察组的总有效率要明显高于对照组,组间差异具有统计学意义(P<0.05)。两组治疗前中医证候积分差异无统计学意义(P>0.05)。两组治疗后与治疗前相比中医证候积分降低;治疗后观察组与对照组相比上述评分降低更加显著,组间差异具有统计学意义(P<0.05)。两组治疗前C反应蛋白(C-reactive protein,CRP)、白介素-6(interleukin-6,IL-6)及肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)相比差异无统计学意义(P>0.05);两组治疗后与治疗前相比CRP、IL-6及TNF-α水平均降低;治疗后观察组与对照组相比上述指标降低更加显著,组间差异具有统计学意义(P<0.05)。两组治疗前后最大流速、搏动指数、阻力指数及时间流速积分相比差异无统计学意义(P>0.05)。观察组与对照组相比每周性生活频率升高、性唤起时间缩短、获得高潮时间缩短、性生活满意度较高,组间差异具有统计学意义(P<0.05)。两组在治疗期间均未出现明显的不良反应。结论清热理血汤治疗湿热瘀结型盆腔炎性疾病后遗症患者可获得较好的临床疗效,缓解中医临床症状,改善炎性因子及血液流变学指标,提高性生活质量。Objective To explore and analyze the curative effect of Qingre Lixue Decoction(清热理血汤)on patients with sequelae of pelvic inflammatory disease and its influence on inflammatory factors and hemorheological indexes.Methods A total of 82 patients with sequelae of pelvic inflammatory disease admitted in our hospital from March 2018 to March 2020 were selected and divided into control group and observation group by random number table,41 cases in each group,and the control group was given Kangfuyan Capsule(康妇炎胶囊)In the treatment,the observation group was treated with Qingre Lixue Decoction on the basis of the control group,and the clinical efficacy,TCM syndrome integral,changes in inflammatory factors and blood rheology indexes,and sexual life quality evaluation were compared between the two groups.Results The total effective rate of the observation group was significantly higher than that of the control group,and the difference between the groups was statistically significant(P<0.05).There was no significant difference in TCM syndrome scores between the two groups before treatment(P>0.05).The scores of TCM syndromes of the two groups decreased after treatment compared with those before treatment.The scores of the observation group decreased more significantly than those of the control group after treatment,and the difference between the groups was statistically significant(P<0.05).There was no significant difference in CRP,IL-6 and TNF-αbetween the two groups before treatment(P>0.05).After treatment,the levels of CRP,IL-6 and TNF-αdecreased in the two groups compared with those before treatment.After treatment in the observation group,compared with the control group,the above indicators decreased more significantly,and the difference between the groups was statistically significant(P<0.05).There was no significant difference in the maximum flow rate,pulsation index,resistance index,and time flow integration between the two groups before and after treatment(P>0.05).Compared with the control group,

关 键 词：清热理血汤 湿热瘀结型 盆腔炎性疾病 后遗症 疗效 炎性因子 血液流变学指标 

分 类 号：R711.33[医药卫生—妇产科学]