脊髓损伤患者小腿肌间静脉丛血栓危险因素的描述性研究  

Risk factors for calf muscle vein thromboses after spinal cord injury

作　　者：张德俭[1] 罗盛飞 杨明亮[3] 杨德刚[3] 王方永[4] 李建军[5] Zhang Dejian;Luo Shengfei;Yang Mingliang;Yang Degang;Wang Fangyong;Li Jianjun(China Emergency Rehabilitation Research Center,Beijing Bo′ai Hospital,Beijing 100068,China;The Second Hospital of Tianjin Medical University,Tianjin 300211,China;Functional Reconstruction Surgery Department,Beijing Bo′ai Hospital,Beijing 100068,China;Spine and Spinal Cord Surgery Department,Beijing Bo′ai Hospital,Beijing 100068,China;China Rehabilitation Research Center,Beijing Bo′ai Hospital,Beijing 100068,China)

机构地区：[1]中国康复研究中心北京博爱医院急诊外科,北京100068 [2]天津医科大学第二医院康复科,天津300211 [3]中国康复研究中心北京博爱医院脊柱脊髓神经功能重建科,北京100068 [4]中国康复研究中心北京博爱医院脊柱脊髓外科,北京100068 [5]中国康复研究中心,北京100068

出　　处：《中华物理医学与康复杂志》2021年第4期342-346,共5页Chinese Journal of Physical Medicine and Rehabilitation

摘　　要：目的分析脊髓损伤住院患者小腿肌间静脉丛血栓(MCVT)的临床资料特点,探讨其防治策略。方法收集423例脊髓损伤住院患者的病历资料,将住院期间发生MCVT的患者分为观察组,未发生MCVT的患者分为对照组,比较两组患者的临床特点。结果筛选MCVT的影响因素,将其纳入Logistic回归分析。结果显示,年龄、脊髓损伤ASIA分级(A-B级)、脊柱融合术、预防性抗凝、PT治疗、同型半胱氨酸>15μmol/L是影响MCVT发生的相关因素。结论脊髓损伤患者MCVT的发生受多种因素影响,包括年龄、脊髓损伤ASIA分级(A~B级)、脊柱融合术和血清同型半胱氨酸水平,积极行预防性抗凝及物理治疗可能会降低MCVT的发生率。Objective To analyze the clinical data on hospitalized spinal cord injury patients with calf muscle vein thromboses(MCVTs)seeking prevention and treatment techniques.Methods The medical records of 423 patients with spinal cord injury were collected.Those with MCVT constituted the observation group,while those without served as controls.Their clinical data were compared.Results The risk factors for MCVT were screened in logistic regression analyses.The results showed that age,an ASIA grade of A or B,spinal fusion,preventive anticoagulation,physiotherapy treatment and a homocysteine level>15μmol/L were risk factors for the occurrence of a MCVT.Conclusions Age,an ASIA grade of A or B,spinal fusion or an elevated serum homocysteine level are all risk factors for MCVT.Active anticoagulation and physical therapy may reduce the risk.

关 键 词：脊髓损伤 小腿肌间静脉丛血栓 血栓性疾病 回顾分析 

分 类 号：R651.2[医药卫生—外科学]