创伤脓毒症研究领域存在的几个关键问题  

Several key scientific issues in research of post-traumatic sepsis

作　　者：梁华平[1] 朱俊宇 胡明冬 Liang Huaping;Zhu Junyu;Hu Mingdong(Department of Wound Infection and Drug,Daping Hospital,Army Medical University,State Key Laboratory of Trauma,Burns and Combined Injury,Chongqing 400042,China;Center of Respiratory and Critical Care Medicine,Department of Gerontology and Secret Service Medicine,Second Affiliated Hospital,Army Medical University,Chongqing 400037,China)

机构地区：[1]陆军军医大学大坪医院野战外科研究部战伤感染与特需药品研究室,创伤烧伤与复合伤国家重点实验室,重庆400042 [2]陆军军医大学第二附属医院呼吸与危重症医学中心,老年与特勤医学科,重庆400037

出　　处：《中华创伤杂志》2021年第5期385-389,共5页Chinese Journal of Trauma

基　　金：军事医学创新工程专项(18CXZ002);校级临床医学科研人才资助项目(2019XLC1011);军事医学前沿创新能力培养计划(2019CXJSC010)。

摘　　要：脓毒症仍然是导致创伤患者晚期死亡的主要“杀手”。创伤后脓毒症研究领域存在的诸多瓶颈问题尚未解决,主要体现在预警研究滞后、预防性干预措施有限及诊断标准不清。笔者着重围绕脓毒症的预警、预防性干预措施及早期诊断标准等三个方面进行分析,指导临床积极应对,以降低创伤后脓毒症所致的晚期病死率,进而提升创伤救治的整体水平。Sepsis remains the leading cause of late death in trauma patients.Many bottleneck problems in the field of post-traumatic sepsis research have not been solved,which are mainly reflected in the lag of early warning research,limited preventive interventions and unclear diagnostic criteria.The authors focus on the early warning of sepsis,preventive intervention measures and early diagnostic criteria to guide the clinical positive response so as to reduce the late mortality caused by post-traumatic sepsis and improve the overall level of trauma treatment.

关 键 词：创伤和损伤 脓毒症 诊断 干预 

分 类 号：R459.7[医药卫生—急诊医学]