不同中医辨证分型与门静脉高压性胃病严重程度的关系  

The Relationship Between Different TCM Syndrome Types and the Severity of Portal Hypertensive Gastropathy

作　　者：杜丽明[1] 李广鉴[1] 孙秋[1] 王文鸽[1] 高媛[1] 李晨 陈朔华 DU U-ming;LI Guang-jian;SUN Qiu;WANG Wen-ge;GAO Yuan;LI Chen;CHEN Shuo-hua(Kailuan General Hospital,Tangshan Hebei 063000,China;Kailuan Employee Health Insurance Center,Tangshan Hebei 063000,China)

机构地区：[1]开滦总医院,河北唐山063000 [2]开滦员工健康保障中心,河北唐山063000

出　　处：《中医药导报》2021年第4期49-52,57,共5页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：河北省中医药管理局科研计划项目(2019265)。

摘　　要：目的:分析不同中医辨证分型与门静脉高压性胃病(PHG)严重程度的关系。方法:对确诊为PHG的260例患者进行中医辨证分型、病情评估,收集患者的化验指标。分析不同中医辨证分型化验指标的组间比较采用单因素方差分析,不同中医辨证分型与PHG严重程度比较使用χ^(2)检验。比较不同中医辨证分型与化验指标的关系及与PHG严重程度的相关性。结果:不同中医辨证分型的hs-CRP、PLT、FIB、TG、GLU比较,差异均有统计学意义(P<0.05)。不同中医辨证分型的PHG轻中重度组间比较,差异有统计学意义(P<0.05),其中,瘀血阻络证发生重度PHG的危险性是肝气郁结证的5.29倍[95%CI(1.16,24.21)]。进一步校正了差异有统计学意义的变量(性别、年龄、肝癌、PLT、CRP、GLU、TG),结果显示瘀血阻络证是发生重度PHG的危险性是肝气郁结证的4.99倍[95%CI(1.04,23.84)]。结论:PHG患者不同中医辨证分型与PHG的严重程度存在相关性。瘀血阻络证较肝气郁结证更容易出现重症。Objective: To analyze the relationship between different TCM syndrome types and the severity of portal hypertensive gastropathy(PHG). Methods: The syndrome differentiation and condition assessment of 260 patients with portal hypertensive gastropathy were conducted, and the laboratory indexes of the patients were collected. Single factor analysis of variance was used for the comparison of different TCM syndrome types, and chi-square test was used to compare the severity of PHG with different TCM syndrome types. Logistic regression analysis was used to analyze the risk of severe PHG in different TCM syndromes. Results: The differences of hs-CRP, PLT, FIB, TG and GLU of different TCM syndrome types were statistically significant(P<0.05). There were statistically significant differences in PHG of mild, moderate and severe groups, among different TCM syndromes(P<0.05) among which, the risk of severe PHG caused by blood stasis syndrome was 5.29 times higher than that caused by liver Qi stagnation syndrome [95%CI(1.16, 24.21)]. The variables with statistically significant differences(gender, age, liver cancer, PLT, CRP, GLU and TG) were further adjusted, and the results showed that the risk of severe PHG in blood stasis syndrome was 4.99 times higher than that in liver Qi stagnation syndrome [95% CI(1.04, 23.84)]. Conclusion: There is a correlation between different TCM syndromes and the severity of portal hypertensive gastropathy. The syndrome of blood stasis blocking collateral is more likely to be severe than the syndrome of liver Qi stagnation.

关 键 词：中医辨证分型 门静脉高压性胃病 严重程度 

分 类 号：R256.42[医药卫生—中医内科学]