基于fMRI技术针刺神门穴脑成像研究进展  

Research Progress on Brain Imaging of Acupuncture at Shenmen (HT7) based on fMRI Technology

作　　者：李晓陵[1] 李冰昕 李昂[3] 王丰[1] 曹丹娜[1,2] 刘晓慧 蔡丽娜 姜晓旭 崔璇 LI Xiao-ling;LI Bing-xin;LI Ang;WANG Feng;CAO Dan-na;LIU Xiao-hui;CAI Li-na;JIANG Xiao-xu;CUI Xuan(First Afiliated Hospital,Heilongiang University of Chinese Medicine,Harbin Heilongjiang 150040,China;Craduate School of Heilongiang University of Chinese Medicine,Harbin Heilongjiang 150040,China;Public Health College of Harbin Medical Universily,Harbin Heilongiang 150081,China)

机构地区：[1]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040 [2]黑龙江中医药大学研究生院,黑龙江哈尔滨150040 [3]哈尔滨医科大学公共卫生学院,黑龙江哈尔滨150081

出　　处：《中医药导报》2021年第4期112-115,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金面上项目(81973930,81373714);黑龙江省自然科学基金项目(LH2020H103,H2016081);哈尔滨市科技创新人才优秀学科带头人基金(2016RAXYJ096);教育部“春晖计划”(Z2009-1-15030);哈尔滨市科技创新人才专项资金项目(2017RAQXJ180);黑龙江省中医药科研项目(ZHY12-Z046);黑龙江省卫生厅科研课题(2012-346)。

摘　　要：通过整理、阅读与分析基于功能磁共振成像(f MRI)技术研究针刺神门穴的相关文献,探索生理与病理状态下针刺神门穴特异性激活脑区的情况。手少阴心经神门穴激活的脑区与经络循行密切相关,会形成复杂协调功能连接效应,激活的脑区多与自身情绪控制与情绪加工相关,印证了"心主神明"的中医理论。运用f MRI技术在无创条件下分析神经系统内的化学变化及其神经活动或行为的相关性,揭示针刺神门穴治疗阿尔茨海默病、失眠症及精神发育迟滞等神志方面疾病内在疗效机制。f MRI具有可精确定位的时空分辨性,结合多样化数据处理方法,以功能分化和功能整合为处理原则,为针刺脑效应提供更广泛的理论支持。The specific activation of brain regions by acupuncture at Shenmen point under physiological and pathological conditions was explored through systematically collating, studying and analyzing the relevant literature on acupuncture at Shenmen based on functional magnetic resonance imaging(fMRI). The activated brain areas of Shenmen point of hand Shaoyin heart meridian were closely related to the circulation of meridians and collaterals, which will form a complex coordination function connection effect. The activated brain areas were mostly related to their own emotional control and emotional processing, which confirmed the traditional Chinese medicine theory of "heart xin zhu shen ming". fMRI technique was used to analyze the chemical changes and the correlation of nerve activity or behavior in the nervous system under non-invasive conditions, and to reveal the internal therapeutic mechanism of acupuncture at Shenmen point in the treatment of mental diseases such as Alzheimer’s disease, insomnia and mental retardation. fMRI has the space-time resolution which can be accurately located, combined with a variety of data processing methods, with functional differentiation and functional integration as the processing principle, to provide more extensive theoretical support for acupuncture brain effect.

关 键 词：针刺 神门穴 功能磁共振成像 脑 研究进展 

分 类 号：R245.2[医药卫生—针灸推拿学]