过山蕨中1个新结构三萜皂苷的结构鉴定  

A new 9,19-cycloartane glycoside from Asplenium ruprechtii

作　　者：江志波 陈靖枝 郭欢欢 胡运琪 郭鑫 马晓莉 杨静玲 王芳 张岱州 吴秀丽[3] JIANG Zhi-bo;CHEN Jing-zhi;GUO Huan-huan;HU Yun-qi;GUO Xin;MA Xiao-li;YANG Jing-ling;WANG Fang;ZHANG Dai-zhou;WU Xiu-li(School of Chemistry and Chemical Engineering,Key Laboratory of Chemical Engineering and Technology of State Ethnic Affairs Commission,North Minzu University,Yinchuan 750021,China;Institute of Traditional Chinese Medicine,Shandong Academy of Pharmaceutical Sciences,Ji'nan 250101,China;College of Pharmacy,Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]北方民族大学化学与化学工程学院国家民委化工技术重点实验室,宁夏银川750021 [2]山东省药学科学院山东省化学药物重点实验室,山东济南250101 [3]宁夏医科大学药学院,宁夏银川750004

出　　处：《中国中药杂志》2021年第5期1155-1159,共5页China Journal of Chinese Materia Medica

基　　金：“西部青年学者”(西部之光)项目(XAB2019AW05);宁夏自治区重点研发计划项目(2020BFG02006)。

摘　　要：对过山蕨水提物化学成分进行了研究。采用硅胶柱色谱、凝胶(Sephadex LH-20)柱色谱、制备高效液相色谱等方法分离纯化过山蕨水提物中的化学成分,并根据波谱数据进行结构鉴定。从中分离鉴定了5个化合物,分别为aspleniumside G(1),trans-p-coumaric acid(2),trans-p-coumaric acid 4-O-β-D-glucoside(3),cis-p-coumaric acid 4-O-β-D-glucoside(4)和(E)-ferulic acid-4-O-β-D-glucoside(5)。其中化合物1为新结构三萜皂苷类化合物。Chemical constituents of water extracts of Asplenium ruprechtii were investigated.Five compounds were isolated by silica gel,Sephadex LH-20 gel column chromatographies and preparative HPLC,and their structures were identified by various spectral analyses as aspleniumside G(1),trans-p-coumaric acid(2),trans-p-coumaric acid 4-O-β-D-glucoside(3),cis-p-coumaric acid 4-O-β-D-glucoside(4),and(E)-ferulic acid-4-O-β-D-glucoside(5).Among them,compound 1 is a new 9,19-cycloartane glycoside.

关 键 词：过山蕨 化学成分 分离鉴定 三萜皂苷 

分 类 号：R284.1[医药卫生—中药学]