婴儿血流感染盐单胞菌1例  

A case report of Halomonas sp. isolated from an infant bloodstream infection

作　　者：刘敏雪 黄丽英[1] 梁嘉慧 曾尚娟[1] 岑贞娇[1] 李萌[2] 黄战[1] 阮佳玲 张欢 王双杰[1] LIU Minxue;HUANG Liying;LIANG Jiahui;ZENG Shangjuan;CEN Zhenjiao;LI Meng;HUANG Zhan;RUAN Jialing;ZHANG Huan;WANG Shuangjie(The Maternal&Child Health Hospital of Guangxi Zhuang Autonomous Region,Nanning 530000,Guangxi Zhuang Autonomous Region,China;The First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi Zhuang Autonomous Region,China)

机构地区：[1]广西壮族自治区妇幼保健院,南宁530000 [2]广西医科大学第一附属医院,南宁530021

出　　处：《微生物与感染》2020年第6期398-402,共5页Journal of Microbes and Infections

基　　金：广西壮族自治区卫生厅自筹经费科研课题(Z20190836),广西壮族自治区妇幼保健院2018年“育苗计划”青年项目(GXWCH-YMJH-2018008)。

摘　　要：盐单胞菌(Halomonas)是革兰阴性杆菌,有嗜盐特性,多从含盐水环境中分离得到。国内、外少见盐单胞菌感染相关报道。本文报道就诊于广西壮族自治区妇幼保健院的1例婴幼儿血流感染盐单胞菌病例,患儿感染症状典型,表现为发热、C反应蛋白升高,并伴随肺部炎症。来自该病例的盐单胞菌因生长速度慢,生化、质谱数据库局限而难以鉴定,最终经16S rRNA基因测序,确定为盐单胞菌。本文对该例感染的盐单胞菌生长情况及引起的临床感染特征进行分析,期望对减少临床盐单胞菌感染的漏检有所帮助,并为临床医师提供诊治参考。Halomonas sp.is a Gram-negative,halophilic bacillus,present in saline environments.The report about Halomonas sp.infection is rare.Here we reported a case of an infant suffered Halomonas sp.bloodstream infection that hospitalized in the Maternal&Child Health Hospital of Guangxi Zhuang Autonomous Region.The symptoms of this infant were fever,C-reactive protein elevation and following pulmonary inflammation.Because of slow growth rate and limited database scope,this Halomonas sp.could be identified by16S rRNA gene sequencing but not by biochemical methods or MALDI-TOF MS.This study might help clinical diagnosis and treatment of Halomonas sp.infections.

关 键 词：盐单胞菌 感染 鉴定 实验室检验 

分 类 号：R446.5[医药卫生—诊断学]