苯醚甲环唑水凝胶的缓释性  

Release behavior of diphenoxazole hydrogel

作　　者：赵丽娟[1,2] 张鹏九 高越 张洪 ZHAO Lijuan;ZHANG Pengjiu;GAO Yue;ZHANG Hong(College of Plant Protection,Shanxi Agricultural University,Shanxi Key Laboratory of Integrated Pest Management in Agriculture,Institute of Plant Protection,Taiyuan,030031,China;Department of Biology,Xinzhou Normal University,034000,China;Shanxi Academy of Analytical Sciences,Taiyuan,030031,China)

机构地区：[1]山西农业大学植物保护学院,农业有害生物综合治理山西省重点实验室,太原030031 [2]忻州师范学院生物系,034000 [3]山西省分析科学研究院,太原030031

出　　处：《环境化学》2021年第4期1292-1294,共3页Environmental Chemistry

基　　金：农业有害生物综合治理山西省重点实验室开放基金(YHSW2019002),忻州师范学院学术带头人和忻州师范学院博士科研启动金资助.

摘　　要：本文采用液质联用仪、磁力搅拌器、电子透镜测定了水凝胶的半衰期、胶凝时间、水分蒸发率、溶胀率、形态结构.结果显示苯醚甲环唑水凝胶在24 h后仍然可以维持15%以上的水分,12 h以内仍然保持良好的溶胀率,苯醚甲环唑可以均匀的分布在水凝胶微孔结构内,其半衰期为26.4 d.氧化魔芋葡聚糖和羟甲基化壳聚糖制成的苯醚甲环唑水凝胶制剂可以有效的愈合植物伤口并延长药效.The half-life,gelation time,water lost,swelling rate and microcosmic morphology of the hydrogel were determined by liquid chromatography-mass spectrometry,magnetic stirrer and scanning electron microscope.The results showed that diphenoxazole hydrogel could maintain more than 15%moisture content after 24 h,and maintain good swelling rate within 12h;Diphenoxazole can be evenly distributed in the microporous structure of the hydrogel,with a half-life of 26.4 d.The diphenoxazole hydrogel made from Oxidized Koniac Glucomannan(OKGM)and Carboxymethyl chitosan(CMCS)can effectively heal plant wounds and prolong the efficacy.

关 键 词：苯醚甲环唑 水凝胶 缓释性 

分 类 号：TQ450.4[化学工程—农药化工] TQ427.26