昼夜节律失调性睡眠觉醒障碍的治疗策略  

Strategies for the treatment of circadian dysrhythmic sleep and wakefulness disorder

作　　者：吴伟[1] 邓丽影[1] WU Wei;DENG Liying(Department of Neurology,the Second Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi,China)

机构地区：[1]南昌大学第二附属医院神经内科,江西南昌330006

出　　处：《中国临床药理学与治疗学》2021年第5期511-515,共5页Chinese Journal of Clinical Pharmacology and Therapeutics

基　　金：国家自然科学基金(地区科学基金项目)(31860293)。

摘　　要：昼夜节律失调性睡眠觉醒障碍是一组由于昼夜节律失调而导致的睡眠觉醒紊乱,由于患者主诉入睡困难、早醒、日间思睡等常被误诊为失眠而误治。美国睡眠医学会(AASM)于2014年更新了诊断标准,2015年又发布了相关治疗指南。近年,多个国家发布了相关临床实践指南或共识。昼夜节律失调性睡眠觉醒障碍的治疗方法不同于常见的睡眠觉醒障碍,重点是采用非药物的方法调控昼夜节律,重置24 h睡眠觉醒的正常节律。本文重点介绍其治疗策略及方法。Circadian rhythm sleep-wake disorders(CRSWDs)is a group of sleep-wake disorders caused by circadian rhythm disorder.Patients complain of difficulty in falling asleep,early waking,daytime drowsiness,which are often misdiagnosed and delayed for treatment.The American Academy of Sleep Medicine(AASM)updated the diagnostic criteria in 2014,and issued relevant treatment guidelines in 2015.In recent years,many countries have issued relevant clinical practice guidelines or consensus.The treatment of circadian rhythm sleep-wake disorder is different from the common sleep-wake disorder,with the focus on non-pharmacologic circadian rhythm regulation to reset the normal 24-hour sleep-wake rhythm.This article mainly introduces its treatment strategy and method.

关 键 词：昼夜节律 睡眠觉醒障碍 光照 行为管理 

分 类 号：Q428[生物学—神经生物学] R388.63[生物学—生理学]