等比重与重比重罗哌卡因对剖宫产母婴影响的比较  

Comparison of the effects of isobaric and hyperbaric ropivacaine on mother and infant after cesarean section

作　　者：佟玲玲[1] 刘丽芳 李凯[3] TONG Lingling;LIU Lifang;LI Kai(Department of Obstetrics and Gynecology,China Japan Union Hospital of Jilin University,Jilin,Changchun 130021,China;Department of Anesthesiology,Jinzhou Central Hospital,Liaoning,Jinzhou 121000,China;Department of Anesthesiology,China Japan Union Hospital of Jilin University,Jilin,Changchun 130021,China)

机构地区：[1]吉林大学中日联谊医院妇产科,吉林长春130021 [2]辽宁省锦州市中心医院麻醉科,辽宁锦州121000 [3]吉林大学中日联谊医院麻醉科,吉林长春130021

出　　处：《中国医药科学》2021年第10期82-84,88,共4页China Medicine And Pharmacy

基　　金：吉林省卫生科研人才专项项目(2019SCZ063)。

摘　　要：目的比较等比重或重比重罗哌卡因腰麻对产妇血流动力学及胎儿的影响。方法纳入2018年9月至2019年6月择期剖宫产产妇100例,随机分为两组,重比重组(H组)为1%罗哌卡因2 ml与10%葡萄糖1 ml配制,等比重组(Ⅰ组)为1%罗哌卡因2 ml与脑脊液1 ml配制,注射腰麻药物容积均为2.2 ml。比较两组术中血流动力学,去氧肾上腺素、恶心、呕吐、脐动脉血pH值及1 min Apgar评分。结果两组一般资料、脐血pH值及1 min Apgar评分比较,差异无统计学意义(P>0.05)。与I组相比,H组去氧肾上腺素次数增多,呕吐发生率增多,差异有统计学意义(P<0.05)。结论等比重罗哌卡因腰麻后产妇发生低血压、恶心、呕吐等症状更少,且对胎儿血pH值及Apgar评分无影响。Objective To compare the effects of spinal anesthesia with isobaric or hyperbaric ropivacaine on puerpera and fetus.Methods A total of 100 cases underwent elective cesarean section from September 2018 to June 2019 were included.They were randomly divided into two groups.The heavyweight ropiracaine group(group H)was prepared with 2 ml ropivacaine(1%)and 1mL glucose(10%),and the isobaric group(group I)was prepared with 2 mL ropivacaine(1%)and 1 mL cerebrospinal fluid(1%).The volume of injected drugs for spinal anesthesia was 2.2 mL.The intraoperative hemodynamics,the phenylephrine,the nausea,the vomiting,the pH value of umbilical artery blood and 1 min Apgar score of two groups were compared.Results There were no significant differences in general data,PH value of umbilical cord blood and 1min Apgar score between the groups(P>0.05).Compared with group I,the frequency of phenylephrine and the incidence of vomiting in group H increased significantly(P<0.05).Conclusion After spinal anesthesia with isobaric ropivacaine,there were fewer symptoms such as hypotension,nausea and vomiting in parturients,and there was no effect on pH value of fetal blood and Apgar score.

关 键 词：等比重 重比重 罗哌卡因 剖宫产 

分 类 号：R719[医药卫生—妇产科学] R614[医药卫生—临床医学]