质子束治疗中Bragg峰分布特性的SRIM模拟研究  

Simulation on the bragg peak distribution based on SRIM in proton therapy

作　　者：田丽霞 房冰冰[2] 朱光昊 杜震 TIAN Lixia;FANG Bingbing;ZHU Guanghao;DU Zhen(School of Nuclear Science and Engineering,East China University of Technology,Nanchang 330013 China;The Engineering&Technical College of Chengdu University of Technology)

机构地区：[1]东华理工大学核科学与工程学院,江西南昌330013 [2]成都理工大学工程技术学院

出　　处：《中国辐射卫生》2021年第1期91-93,122,共4页Chinese Journal of Radiological Health

基　　金：国家自然科学基金(12075056);核技术应用教育部工程研究中心开放基金资助项目(HJSJYB2015-12)。

摘　　要：目的在质子治疗中,对SRIM程序在模拟质子Bragg峰分布特性方面进行探讨。方法基于SRIM程序,对50~250 MeV的不同能量的质子束入射到水、聚苯乙烯,有机玻璃以及铝、铁等不同介质中的输运过程进行了模拟分析,对不同的质子入射能量、介质材料及厚度与其Bragg峰深度的关系进行了研究,并与专业的蒙特卡罗程序Fluka2011以及MCNPX模拟结果进行对比。结果随着入射质子能量的增加,其Bragg峰深度逐步增大并伴随展宽增大;相同质子入射能量下不同介质的Bragg峰深度与水中的Bragg峰深度之比随质子的入射能量变化不大,近似为一常数,所得结果与成熟的Fluka及MCNPX程序模拟值是一致的。结论 SRIM程序在模拟质子束输运方面其精度是可行的,对于初学者可以采用简单易学的SRIM来替代繁琐的Fluka及MCNPX程序。Objective To discuss the distribution characteristics of the Bragg peak in proton therapy using the SRIM code.Methods Based on the SRIM code, the transport processes of a high-energy proton beam injecting into different materials(H2O, C2 H6 O、C8H8、Al and Fe)with incident energies of 50 MeV~250 MeV have been simulated and analyzed. And the relationship between the incident energies, different materials and thickness, and the depth of the Bragg peak was also discussed when the protons injected into different materials and compared with the simulation results of professional Monte Carlo code, such as Fluka 2011 and MCNPX. Results The simulation results indicate that the depths of the Bragg peak increase gradually and the peaks broaden with the increase of incident proton energies for different materials;The ratio of the depth of the Bragg peak in different materials to that in water under the same incident energy changes little and is approximately a constant which doesn’t depend on the proton incident energy. A good consistency was found between the results and those obtained using Fluka and MCNPX programs. Conclusion The simulation accuracy of the SRIM on the proton beam transport is acceptable, and is suitable for the beginning learners.

关 键 词：SRIM Bragg峰 质子 

分 类 号：R815.2[医药卫生—放射医学]