阳江地区丙型肝炎病毒基因型分布特点的分析研究  

Analysis of the distribution characteristics of hepatitis C virus genotypes in Yangjiang area

作　　者：陈兴 钟冬福 梁桂兰 陈颖 CHEN Xing;ZHONG Dong-fu;LIANG Gui-lan(Department of Infectious Diseases,Yangjiang Public Health Hospital,Yangjiang 529500,China)

机构地区：[1]阳江市公共卫生医院感染科,529500

出　　处：《中国现代药物应用》2021年第10期228-230,共3页Chinese Journal of Modern Drug Application

基　　金：阳江市医疗卫生类科技计划项目(项目编号:SF2020126)。

摘　　要：目的研究阳江地区丙型肝炎病毒(HCV)基因型分布特点及疫情报告情况,为制订防治策略提供依据。方法分析2019年11月~2021年2月阳江地区丙型病毒性肝炎的疫情报告资料。结果405例送检感染者共有7类检测结果,共检出6种基因型。检测结果以6a型为主、占比49.6%,其次为3a型、占比25.2%,1b型、占比19.3%,3b型、占比4.4%;另外,有2例2a型、2例3a,6b混合型;有2例可检测到丙型肝炎病毒核糖核酸(HCV RNA)但型别未明。不同HCV基因型患者的年龄比较,差异无统计学意义(P>0.05)。结论阳江地区HCV感染基因型分布以6a型以及3a型为主,加强遏制毒品违法犯罪活动力度、重视HCV筛查,对于控制该地区HCV的传播至关重要。Objective To study the genotype distribution and epidemic situation of hepatitis C virus(HCV)in Yangjiang area in order to provide a basis for the formulating control strategy.Methods The epidemic report data of viral hepatitis C in Yangjiang area from November 2019 to February 2021 was analyzed.Results There were 7 kinds of results in 405 cases,and 6 genotypes were detected.The test results are mainly type 6a,accounting for 49.6%,followed by type 3a,accounting for 25.2%,type 1b,accounting for 19.3%,and type 3b,accounting for 4.4%.In addition,there were 2 cases of type 2a,2 cases of mixed type type 3a,6b;2 cases of hepatitis C virus ribonucleic acid(HCV RNA)can be detected but the type was unknown.There was no statistically significant difference in the age of patients with different HCV genotypes(P>0.05).Conclusion The genotype distribution of HCV infection in Yangjiang area is mainly type 6a and type 3a.It is of great importance to strengthen the efforts to curb illegal drug activities and pay attention to HCV screening,so as to control the spread of HCV in Yangjiang area.

关 键 词：丙型肝炎病毒 基因型 疫情报告 吸毒 

分 类 号：R512.63[医药卫生—内科学]