神经内镜手术治疗透明隔囊肿合并韦尔加腔的临床预后评价研究  

Analysis of the clinical outcomes of symptomatic septum pellucidum cyst with Cavum Vergae treatedby neuroendoscopy

作　　者：李星辉 马国佛[2] 乔宁 赵澎[2] 桂松柏[2] Li Xinghui;Ma Guofo;Qiao Ning;Zhao Peng;Gui Songbai(Department of Neurosurgery,Beijing Daxing District People's Hospital,Beijing 102600,China;Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)

机构地区：[1]北京市大兴区人民医院神经外科,北京102600 [2]首都医科大学附属北京天坛医院神经外科,100070

出　　处：《神经疾病与精神卫生》2021年第4期271-275,共5页Journal of Neuroscience and Mental Health

摘　　要：目的通过构建透明隔囊肿合并韦尔加腔患者临床症状评价体系以及术前、术后囊肿体积变化,找出可以定量预测透明隔囊肿合并韦尔加腔患者术后预后的评价指标。方法纳入9例经MRI确诊的透明隔囊肿合并韦尔加腔患者,首先通过术前术后磁共振影像资料,计算患者囊肿缩小率;其次,通过患者临床症状特点,对各项临床症状予评分,建立临床症状评分体系;最后找出临床症状与囊肿客观影像学定量数据之间的相关性。结果术后临床症状评分、囊肿体积均明显低于术前,差异均有统计学意义(t'值分别为6.36、5.06,均P<0.01)。相关性分析结果表明,术前患儿囊肿体积与术前临床症状评分无明显相关性(r=0.018,P>0.05),术后患儿临床症状评分与术后囊肿体积大小无明显相关性(r=0.520,P>0.05);术后临床症状评分改善与囊肿体积缩小率呈正相关(r=0.843,P=0.009),术后临床症状评分改善与术后囊肿体积呈负相关关系(r=-0.738,P=0.037)。结论神经内镜手术作为症状性透明隔囊肿合并韦尔加腔的手术方式之一,其术后症状改善效果明显。其中,术后囊肿缩小率及术后囊肿体积可以作为症状性透明隔囊肿合并韦尔加腔患者术后预后的独立定量预测指标。Objective By constructing the clinical symptom evaluation system of patients with Cavum Septum Pellucidum(CSP)combined with Cavum Vergae(CV),and the changes of cysts volume before and after operation,we want to find out the evaluation indicators that can quantitatively predict the prognosis of patients with CSP combined with CV.Methods Nine patients with CSP combined with CV diagnosed by MRI were recruited.Firstly,the reduction rate of cyst was calculated by preoperative and postoperative MRI data.Secondly,according to the characteristics of clinical symptoms,the clinical symptoms were scored,and the clinical symptom scoring system was established.Finally,the correlation between clinical symptoms and objective imaging quantitative data of cyst shall be find out.Results The clinical symptom scores and cyst volume after operation were significantly lower than those before operation,and the differences were statistically significant(t'values are 6.36 and 5.06,respectively,P<0.01).There was no significant correlation between preoperative cyst volume and preoperative clinical symptom scores of children(r=0.018,P>0.05).There was no significant correlation between clinical symptom score and cyst volume(r=0.520,P>0.05).There was a positive correlation between the improvement of clinical symptom score and the reduction rate of cyst volume(r=0.843,P=0.009).There was a negative correlation between the improvement of clinical symptom score and the volume of cyst(r=-0.738,P=0.037).Conclusions As one of the surgical methods of CSP combined with CV,neuroendoscopic surgery can significantly improve the postoperative symptoms.Postoperative cyst reduction rate and postoperative cyst volume can be used as independent quantitative predictors of the postoperative prognosis of patients with symptomatic CSP with CV.

关 键 词：透明隔囊肿 韦尔加腔 内镜手术策略 临床症状评分 囊肿缩小率 

分 类 号：R651[医药卫生—外科学]