补肾消癃方联合经尿道等离子前列腺电切术治疗肾虚血瘀型良性前列腺增生症临床观察  

Clinical value of Bushen Xiaolong Prescription combined with transurethral plasmakinetic resection of prostate on benign prostatic hyperplasia of kidney deficiency and blood stasis syndrome

作　　者：李翔[1] 彭煜[1] 胡晓华[1] 朱文静[1] 周桂平[1] LI Xiang;PENG Yu;HU Xiaohua;ZHU Wenjing;ZHOU Guiping(Department of Urology,Yueyang Hospital of Integrated Traditional Chinese and Western medicine,Shanghai University of Traditional Chinese medicine,Shanghai 200437)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院泌尿外科,上海200437

出　　处：《河北中医》2021年第2期265-269,共5页Hebei Journal of Traditional Chinese Medicine

基　　金：上海市中医药领军人才计划[编号:ZY(2018—2020)-RCPY-1017];上海市进一步加快中医药事业发展三年行动计划(2018年—2020年)项目:泌尿专科。

摘　　要：目的观察补肾消癃方联合经尿道等离子前列腺电切术治疗肾虚血瘀型良性前列腺增生症(BPH)的临床疗效。方法将94例肾虚血瘀型BPH患者按照随机数字表法分为2组。对照组47例予经尿道等离子前列腺电切术治疗,治疗组47例在对照组治疗基础上联合补肾消癃方治疗3周。比较2组治疗前后国际前列腺症状评分(IPSS)、国际勃起功能指数(IIEF-5)、夜尿频率、最大尿流率、残余尿量、生活质量综合评定问卷(GQOLI-74)评分,比较2组术后3 d疼痛视觉模拟评分(VAS),并统计住院时间、疗效及并发症发生情况。结果治疗组总有效率97.87%(46/47),对照组总有效率82.98%(39/47),治疗组疗效优于对照组(P<0.05)。治疗后2组IPSS均较本组治疗前降低(P<0.05),IIEF-5评分均升高(P<0.05),且治疗后治疗组IPSS低于对照组(P<0.05),IIEF-5评分高于对照组(P<0.05)。治疗后2组夜尿频率、残余尿量均较本组治疗前降低(P<0.05),最大尿流率升高(P<0.05),且治疗后治疗组夜尿频率、残余尿量均低于对照组(P<0.05),最大尿流率高于对照组(P<0.05)。治疗组疼痛VAS低于对照组(P<0.05),住院时间短于对照组(P<0.05)。治疗后2组GQOLI-74各项评分均较本组治疗前升高(P<0.05),且治疗后治疗组均高于对照组(P<0.05)。治疗组并发症发生率低于对照组(P<0.05)。结论补肾消癃方联合经尿道等离子前列腺电切术治疗肾虚血瘀型BPH能提高患者临床疗效,前列腺功能恢复良好,生活质量显著提升,并发症发生率低,安全性高,值得推广应用。Objective To observe the clinical value of Bushen Xiaolong Prescription combined with transurethral plasmakinetic resection of prostate in treatment of benign prostatic hyperplasia(BPH)of kidney deficiency and blood stasis syndrome.Methods Totally 94 patients with BPH of kidney deficiency and blood stasis syndrome were randomly divided into two groups,47 cases per group.The control group was treated with transurethral plasmakinetic resection of prostate,the treatment group was additionally Bushen Xiaolong Prescription on the basis of the control group.Both groups were treated for 3 weeks.The international prostate symptom score(IPSS),international index of erectile function(IIEF-5),nocturia frequency,maximum urine flow rate,residual urine volume and quality of life questionnaire(GQOLI-74)score were compared between the two groups before and after treatment;3 days after operation,the pain visual analogue score(VAS)was compared between the two groups,and the hospitalization time,curative effect and complications were counted.Results The total effective rate in the treatment group was better than that in the control group[97.87%(46/47)vs 82.98%(39/47),(P<0.05),respectively].compared before treatment,IPSS scores in the two groups after treatment were significantly decreased(P<0.05),which in the treatment group were lower than the control group(all P<0.05);IIEF-5 scores in the two groups after treatment were significantly increased(P<0.05),which in the treatment group were higher than the control group(P<0.05);nocturia frequency and residual urine volume in the two groups after treatmentwere significantly decreased(P<0.05),which in the treatment group were lower than the control group(all P<0.05);maximum urine flow rate in the two groups after treatment were significantly increased(P<0.05),which in the treatment group were higher than the control group(P<0.05).After treatment,the pain VAS,hospitalization time in the treatment group were significantly lower or shorter than those in the control group(P<0.05);GQOLI-74 sc

关 键 词：前列腺增生 肾虚 血瘀 经尿道前列腺切除术 中西医结合疗法 

分 类 号：R697.305.8[医药卫生—泌尿科学]