内镜下注射治疗在原发性膀胱输尿管反流的应用及研究进展  

Applications and research advances of endoscopic injection therapy for primary vesicoureteral reflux

作　　者：吴泠 陈嘉波[1] Wu Ling;Chen Jiabo(Department of Pediatric Surgery,First Affiliated Hospital,Guangxi Medical University,Nanning 530000,China)

机构地区：[1]广西医科大学第一附属医院小儿外科,南宁530000

出　　处：《中华小儿外科杂志》2021年第5期468-471,共4页Chinese Journal of Pediatric Surgery

基　　金：广西医疗卫生适宜技术开发与推广应用项目(S2019104)。

摘　　要：膀胱输尿管反流(vesicoureteral reflux,VUR)是常见的儿童泌尿系统畸形。内镜注射治疗应用于低级别原发性VUR,在欧美国家是首选和主流方法,在国内尚方兴未艾。右旋糖酐/透明质酸共聚物(dextranomer/hyaluronic acid copolymer,Dx/HA)是业内公认安全有效的注射剂,膀胱扩张注射术(hydrodistention implantation technique,HIT)及Double HIT注射术是常用的操作方法。内镜注射治疗安全、有效、微创,能够有效预防及控制VUR所导致的尿路感染、减少肾瘢痕形成、防止肾功能损害,应用前景广泛。Vesicoureteral reflux(VUR)is a common malformation of urinary system in children.Endoscopic injection has been a first choice for primary low-level VUR in Europe and North America.It is gaining popularity in China.Dextranomer/hyaluronic acid copolymer(Dx/HA)is widely known as a safe and effective filler.Hydrodistention implantation technique(HIT)and Double HIT injection are commonly applied.With the curative properties of preventing and controlling urinary tract infections,minimizing renal scarring and avoiding renal function damage,endoscopic injection treatment is safe,effective and mini-invasive.Its overall success rate is similar to that of surgery.

关 键 词：儿童 膀胱输尿管反流 内镜 注射 

分 类 号：R726.9[医药卫生—儿科]