甲状腺乳头状癌超声造影血流灌注参数与微血管密度、微血管面积的相关性分析  

Correlation analysis of contrast-enhanced ultrasound perfusion parameters with microvessel density and microvessel area in papillary thyroid carcinoma

作　　者：吕娟[1] 万静[1] 张利[1] Lv Juan;Wan Jing;Zhang Li(Department of Ultrasound,People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang 830000,China)

机构地区：[1]新疆维吾尔自治区人民医院超声科,新疆乌鲁木齐830000

出　　处：《影像研究与医学应用》2021年第8期16-17,20,共3页Journal of Imaging Research and Medical Applications

基　　金：新疆维吾尔自治区自然科学基金面上项目(2017D01C120)。

摘　　要：目的:探究甲状腺乳头状癌(papillary carcinoma of thyroid gland,PTC)超声造影血流灌注参数与微血管密度(microvascular density,MVD)、微血管面积(microvascular area,MVA)的相关性情况。方法:选取2018年1月—2020年12月时段我院接收的74例PTC患者为对象,根据病灶情况对所选病例进行分设,即≤1cm组(n=29)、≥2cm(n=45)组;另外,所选病例还可根据颈部淋巴结病例结果分设为未转移组(n=44)、转移组(n=30)。结果:在PTC患者中,较≤1cm组,≥2cm组的AUS和Peak、MVA和MVD数据评分结果更高;较转移组,未转移组的AUS和Peak、MVA和MVD数据评分结果更低(P<0.05)。结论:AUC、Peak作为超声造影定量参数,能将PTC的MVA和MVD情况有效反映出来,可对肿瘤微血管生成情况无创性评价,对评估PCT和其预后有重要作用。Objective To explore the correlation between blood flow perfusion parameters of contrast-enhanced ultrasound and microvascular density(MVD)and microvascular area(MVA)in papillary thyroid carcinoma(PTC).Methods 74 patients with PTC in our hospital from January 2018 to December 2020 were selected and divided into≤1 cm group(n=29)and≥2 cm group(n=45)according to the lesion conditions;In addition,the selected cases could be divided into non metastasis group(n=44)and metastasis group(n=30)according to the results of cervical lymph node cases.Results In PTC patients,the data scores of Aus and peak,MVA and MVD in≥2 cm group were higher than those in≤1 cm group;The data scores of Aus and peak,MVA and MVD in non metastasis group were lower than those in metastasis group(P<0.05).Conclusion AUC and peak,as quantitative parameters of contrast-enhanced ultrasound,can effectively reflect MVA and MVD of PTC,can noninvasively evaluate tumor angiogenesis,and play an important role in evaluating PCT and its prognosis.

关 键 词：MVA MVD 血流灌注 超声造影 PTC 

分 类 号：R445.1[医药卫生—影像医学与核医学]