43例新型冠状病毒感染流行病学与临床特征分析  

The epidemiology and clinical features of 43 cases with novel coronavirus infection

作　　者：刘星 刘洪艳[2] 谷野[2] 王磊石 田霞[3] 于红[4] 侯春阳[5] 李欣悦 宋冠男 王岩[1] Liu Xing;Liu Hongyan;Gu Ye;Wang Leishi;Tian Xia;Yu Hong;Hou Chunyang;Li Xinyue;Song Guannan;Wang Yan(Science and Education Department,the Sixth People's Hospital of Shenyang,Shenyang 110006,China;Professional Technology Innovation Center of Liaoning Public Health Emergency,the Sixth People's Hospital of Shenyang,Shenyang 110006,China;Rehabilitation Department of Traditional Chinese Medicine,the Sixth People's Hospital of Shenyang,Shenyang 110006,China;Department of Chinese Medical Hepatology,the Sixth People's Hospital of Shenyang,Shenyang 110006,China;Infection Department,the Sixth People's Hospital of Shenyang,Shenyang 110006,China)

机构地区：[1]沈阳市第六人民医院科教科,沈阳110006 [2]沈阳市第六人民医院辽宁省突发公共卫生事件应急救治专业技术创新中心,沈阳110006 [3]沈阳市第六人民医院中医康复科,沈阳110006 [4]沈阳市第六人民医院中医肝病科,沈阳110006 [5]沈阳市第六人民医院感染科,沈阳110006

出　　处：《新发传染病电子杂志》2021年第2期119-124,共6页Electronic Journal of Emerging Infectious Diseases

基　　金：辽宁省突发公共卫生事件应急救治专业技术创新中心研究基金资助项目;沈阳市科技计划项目(YJ2020-9-010)。

摘　　要：目的分析沈阳市新型冠状病毒感染肺炎患者的流行病学及临床特征,为新型冠状病毒肺炎的诊治提供指导。方法收集和分析2020年12月23日至2021年1月26日沈阳市第六人民医院收治的43例确诊新型冠状病毒感染患者的临床资料和治疗情况。结果43例患者中男性14例,女性29例,年龄范围为16~95岁,平均(54.47±17.97)岁;51.2%的患者有基础疾病;86.0%的患者与确诊患者有接触史;潜伏期3~17d;临床表现主要以发热和上呼吸道症状为主,肺部CT多表现为磨玻璃影。重型/危重型患者实验室检查多表现为白细胞计数、C反应蛋白、D二聚体、白介素-6、降钙素原升高,淋巴细胞计数降低。结论沈阳市确诊的新型冠状病毒感染患者具有年龄偏大、既往基础疾病较多、潜伏期相对较长、重型/危重型患者比例较高、危重患者发展迅速等特点。与轻型/普通型患者相比,重型/危重型患者更易并发肝功能、肾功能、凝血功能异常,心肌损害、心肺功能受损以及感染倾向。Objective To analyze the epidemiological and clinical characteristics of the second wave of patients with coronavirus disease 2019(COVID-19)in Shenyang,and to provide guidance for the diagnosis and treatment of COVID-19.Methods The epidemiological and clinical characteristics of 43 patients with COVID-19 were collected and analyzed from December 23,2020 to January 26,2021 in the Sixth People’s Hospital of Shenyang.Results Among the 43 patients,there were 14 males and 29 females,with an average age of(54.47±17.97)years old ranging from 16 to 95 years old;51.2%patients had basic diseases;86%patients had contact history with confirmed patients;the incubation period was 3 to 17 days;the main clinical manifestations of patients were fever and upper respiratory tract symptoms,and the main pulmonary CT manifestation was ground glass opacity.The laboratory examination of severe/critical patients showed that the number of leukocytes,C-reactive protein,D-dimer,interleukin-6 and procalcitonin were increased,and the number of lymphocytes was decreased.Conclusion The epidemic situation in Shenyang has the characteristics of older patients,more previous basic diseases,longer incubation period,higher proportion of severe/critical patients,and rapid disease progression.Compared with mild/common patients,severe/critical patients were more likely to suffer the infection and the damage in liver,kidney,coagulation,myocardium and cardiopulmonary function.

关 键 词：冠状病毒 新型冠状病毒肺炎 流行病学 临床特征 

分 类 号：R563.1[医药卫生—呼吸系统]