结核病患者非去极化肌松药的药效学特点  

Pharmacodynamic characteristics of non-depolarizing muscle relaxants in patients with tuberculosis

作　　者：刘民强[1] 洪凤珠 石浩文[1] 唐怡敏[2] 李志超[1] 何仁亮[1] Liu Minqiang;Hong Fengzhu;Shi Haowen;Tang Yimin;Li Zhichao;He Renliang(Department of Anesthesiology,the Third People's Hospital of Shenzhen,Guangdong Shenzhen 518112,China;Department of Pulmonary Clinic,the Third People's Hospital of Shenzhen,Guangdong Shenzhen 518112,China)

机构地区：[1]深圳市第三人民医院麻醉科,广东深圳518112 [2]深圳市第三人民医院肺科门诊,广东深圳518112

出　　处：《新发传染病电子杂志》2021年第2期160-162,共3页Electronic Journal of Emerging Infectious Diseases

基　　金：广东省自然科学基金(2020A1515010977)。

摘　　要：非去极化肌松药(NDMR)是目前临床应用最为广泛的骨骼肌松弛药。NDMR的药效学特征与多种因素有关,结核病患者因其病理生理特点和患者长期服药治疗可引起肝功能及神经-肌肉系统受损,影响该类药物的阻滞时效。了解结核病患者NDMR的药效学特点,对该类患者围术期个体化用药具有重要意义。Non-depolarizing muscle relaxants(NDMR)are the most widely used skeletal muscle relaxants in clinical practice.The pharmacodynamic characteristics of NDMR are related to many factors.Tuberculosis(TB)patients would cause liver dysfunction and neuro-muscular system damage due to their pathophysiological characteristics and long-term medication treatment,which affects the blocking time of NDMR.To understand the characteristics of tuberculosis on the pharmacology of NDMR is of great significance for individualized medication in perioperative period.

关 键 词：结核病 非去极化肌松药 药效学 

分 类 号：R52[医药卫生—内科学] R969[医药卫生—临床医学]