多囊卵巢综合征患者雄激素代谢异常的研究进展  

Research Progress on Androgen Excess in Polycystic Ovary Syndrome

作　　者：潘雷 徐键[1,2] PAN Lei;XU Jian(Women’s Hospital,Zhejiang University School of Medicine,Hangzhou 310006,China;不详)

机构地区：[1]浙江大学医学院附属妇产科医院,浙江杭州310006 [2]浙江大学医学院附属第四医院

出　　处：《中外医学研究》2021年第12期192-196,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：国家重点研发计划项目(2019YFC0121000)。

摘　　要：多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄期女性的一种常见的生殖内分泌疾病,其病因尚未阐明。雄激素过多是PCOS的诊断要素和重要临床特征,卵巢、肾上腺和外周组织均参与了PCOS雄激素代谢异常的机制。雄激素过多进一步导致或加重了PCOS患者的生殖、代谢障碍。本文就PCOS患者中雄激素代谢异常的发生机制与影响进行综述,以期对雄激素代谢异常与PCOS的关系形成更加全面的认识。Polycystic ovary syndrome (PCOS) is a common endocrine condition among reproductive-age women,yet the cause of PCOS is still unknown.Androgen excess is a chief attribute and diagnostic criteria of PCOS.Ovaries,adrenal gland and peripheral tissues are all involved in the mechanisms of abnormal metabolism of androgens in PCOS.Reproductive dysfunction and metabolic disorders are further induced or aggravated by androgen excess in PCOS.We reviewed the mechanism and role of androgen excess in PCOS in the hope of providing reference to further explore the relationship between androgen excess and PCOS.

关 键 词：多囊卵巢综合征 雄激素 诊断 不孕 

分 类 号：R711.75[医药卫生—妇产科学]