声触诊组织成像量化技术鉴别乳腺良恶性病灶的临床价值  

Clinical value of virtual touch image quantification in differentiating benign and malignant breast lesions

作　　者：贾妍[1] 蒲欢 彭娟[1] 刘娜[1] 徐芬芬 郭瑞强[1] JIA Yan;PU Huan;PENG Juan;LIU Na;XU Fenfen;GUO Ruiqiang(Department of Medical Ultrasound,Renmin Hospital of w uhan University,W uhan 430060.China)

机构地区：[1]武汉大学人民医院超声影像科,武汉市430060

出　　处：《临床超声医学杂志》2021年第5期351-354,共4页Journal of Clinical Ultrasound in Medicine

摘　　要：目的探讨声触诊组织成像量化(VTIQ)技术鉴别乳腺实性病灶良恶性的临床应用价值。方法选取我院经穿刺活检或手术病理确诊的乳腺肿块患者238例,共计254个病灶,其中良性148个,恶性106个。应用VTIQ技术检测乳腺病灶,分析VTIQ成像速度模式图,测量病灶的剪切波速度最大值(Vmax)、最小值(Vmin)及平均值(Vmean);绘制受试者工作特征(ROC)曲线,分析Vmax、Vmin、Vmean鉴别乳腺良恶性病灶的诊断效能。结果 VTIQ成像中,乳腺实性病灶所显示的速度模式彩色编码图可分为5种类型,其中均匀型56个(良性54个,恶性2个)、欠均匀型79个(良性74个,恶性5个)、杂乱型72个(良性17个,恶性55个)、扩散型33个(良性5个,恶性28个)、硬环型14个(良性1个,恶性13个)。Vmax、Vmin、Vmean鉴别乳腺良恶性病灶截断值分别为5.66 m/s、3.53 m/s、4.84 m/s,其对应的敏感性、特异性、准确率、分别为77.4%、91.9%、85.8%,90.6%、87.1%、88.6%,84.0%、93.2%、89.4%,ROC曲线下面积分别为0.937、0.930、0.973,三者ROC曲线下面积比较差异无统计学意义。结论 VTIQ技术可用于乳腺实性病灶良恶性诊断,Vmax、Vmin、Vmean均具有较高的诊断效能。ObjectiveTo investigate the clinical application value of virtual touch image quantification(VTIQ)in differentiating benign and malignant breast solid lesions.MethodsA total of 238 patients with breast mass diagnosed by needle biopsy or surgical pathology in our hospital were selected,including 254 solid breast lesions(148 benign lesions and 106malignant lesions).VTIQ imaging velocity pattern,the maximum shear wave velocity(Vmax),minimum shear wave velocity(Vmin),and average shear wave velocity(Vmean)of breast lesions were detected by VTIQ.Receiver operating characteristic(ROC)curve was drawn to analyze the diagnostic efficacy of Vmax,Vmin and Vmean in differentiating benign and malignant breast lesions.ResultsIn VTIQ imaging,the color coding speed mode of breast solid masses could be divided into 5 types,including 56 lesions were homogeneous type(54 benign and 2 malignant),79 lesions were homogeneous type(74 benign masses and 5 malignant masses),72 lesions were clutter type 7(17 benign and 55 malignant),33 lesions were diffusion type(5 benign and 28 malignant),14 lesions were hard ring(1 benign and 13 malignant).The cut-off values of Vmax,Vmin and Vmean in differentiating benign and malignant breast lesions were 5.66 m/s,3.53 m/s and 4.84 m/s,respectively.The corresponding sensitivity,specificity and accuracy were 77.4%,91.9%,85.8%,90.6%,87.1%,88.6%,84.0%,93.2%,89.4%,respectively.The area under the ROC curve of Vmax,Vmin and Vmean were 0.937,0.930 and 0.973,and the difference was not statistically significant.ConclusionVTIQ can be used in the diagnosis of benign and malignant breast solid lesions,and the Vmax,Vmin,Vmean have good diagnostic efficiency.

关 键 词：声触诊组织成像量化技术 乳腺肿瘤 良恶性 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]