双探头WIZARD2 2470型伽马计数仪定量性能研究  

Quantitative Assessment of the Dual-Probe WIZARD22470 Gamma Counter

作　　者：赵富宽[1] 徐希杰[1] 王燕[1,2] ZHAO Fukuan;XU Xijie;WANG Yan(NHC Key Laboratory of Nuclear Medicine,Jiangsu Key Laboratory of Molecular Nuclear Medicine,Jiangsu Institute of Nuclear Medicine,Wuxi 214063,China;The First Affiliated Hospital of Soochow University,Suzhou 215006,China)

机构地区：[1]国家卫生健康委员会核医学重点实验室,江苏省分子核医学重点实验室,江苏省原子医学研究所,江苏无锡214063 [2]苏州大学附属第一医院,江苏苏州215006

出　　处：《同位素》2021年第3期282-287,共6页Journal of Isotopes

基　　金：“重大新药创制”科技重大专项(2017ZX09304021);江苏省创新能力建设计划项目(BM2018023);江苏省医学重点学科(ZDXKA2016017)。

摘　　要：伽马计数仪是对微量放射性精确测量的主要仪器之一,仪器性能的准确性、实验操作的规范性与实验结果的可靠性、真实性密切相关。为了在使用之前对仪器性能进行系统研究,本研究利用三种正电子核素^(18)F、^(68)Ga和^(89)Zr对双探头WIZARD2 2470型伽马计数仪进行双探头探测效率、伽马计数检测限、检测稳定性,以及与放射性测量线性范围等性能进行系统研究,结果显示:该仪器两个探头探测效率一致;检测时需考虑实际噪声的影响;计数率在1×10^(3)~6×10^(6) min^(-1)范围时,伽马计数率与放射性活度之间线性关系良好、定量精度高、稳定性佳。本研究中建立的伽马计数仪定量性能的系统研究方法,有望为其他实验室类似仪器的规范使用提供参考。Gamma counter is one of the most important instruments for precise quantitative assessment of the radioactivity.The accuracy of instrument performance and standardization of experimental operation are closely related to the reliability and authenticity of experimental results.In this study,three positron nuclides ^(18)F,^(68)Ga and ^(89)Zr were used to systematically evaluate the dual-probe detection efficiency,detection limit,stability and linear range on the dual-probe WIZARD22470 gamma counter.The results suggested that the two probes have the same detection efficiency,and the influence of the environmental background should be considered during the experiment.Good linearity relationship appeared between gamma count and radioactivity in the range of 1×10^(3)-6×10^(6)min^(-1),with excellent quantitative accuracy and stability.The quantitative method of the dual-probe WIZARD22470 gamma counter in this study is expected to provide a reference for the standardized use of similar instruments in other laboratories.

关 键 词：伽马计数仪 计数率 定量性能 双探头 

分 类 号：TL816.3[核科学技术—核技术及应用]