驱动压在肺保护性通气策略中的研究进展  

Research Progress of Driving Pressure in Lung Protective Ventilation

作　　者：罗桓宇 张亚平 谢俊然[1] LUO Huanyu;ZHANG Yaping;XIE Junran(Department of Anesthesiology,Sir Run Run Shaw Hospital,School of Medicine,Zhejiang University,Hangzhou 310000,China)

机构地区：[1]浙江大学医学院附属邵逸夫医院麻醉科,浙江杭州310000

出　　处：《中国医药指南》2021年第11期31-33,共3页Guide of China Medicine

基　　金：国家自然科学基金项目(81701972);浙江省医药卫生科技项目(2021439997)。

摘　　要：肺损伤是机械通气引起的最严重的并发症之一,也是引起术后肺部并发症的潜在因素。其不仅影响患者的康复,延长住院时间,增加医疗费用,甚至增加病死率。肺保护性通气策略对降低机械通气相关肺损伤发挥着重要作用,因而一直是是该领域的研究热点。如何选择合适的通气方式减轻肺损伤,降低术后肺部并发症是目前最值得探讨的问题。目前肺保护性通气策略的研究已取得一定的成果,包括小潮气量、适当的呼气末正压通气以及间断肺复张,但是随着驱动压的提出,如何优化肺保护性通气策略仍存在诸多争议,在临床中的应用尚无一致意见,本文将对驱动压在肺保护性通气策略中的研究现状作一综述。Lung injury is one of the most serious complications of mechanical ventilation and a potential cause of postoperative pulmonary complications.It not only affects patients'recovery,prolongs hospitalization time,increases medical expenses and even increases mortality.Lung protective ventilation strategy plays an important role in reducing ventilator-related lung injury and has been a hot topic in this field.How to choose an appropriate ventilation method to reduce lung injury and reduce postoperative pulmonary complications is the most worthy of discussion.At present,the research of lung protective ventilation strategy has made some achievements,including small tidal volume and proper positive end-expiratory pressure and recruitment maneuvers.With the concept of driving pressure,how to optimize the lung protective ventilation strategy is still controversy.There is no consensus regarding in the clinical application.This article reviews the research status of the pressure in the lung protective ventilation strategy.

关 键 词：驱动压 肺保护性通气 肺部并发症 综述 

分 类 号：R614[医药卫生—麻醉学] R56[医药卫生—外科学]