氟康唑、制霉菌素+碳酸氢钠治疗40例小儿鹅口疮的效果观察  

Observation on the Effect of Fluconazole,Nystatin and Sodium Bicarbonate in the Treatment of 40 Cases of Infantile Thrush

作　　者：张永盛 ZHANG Yongsheng(Shaxian General Hospital of Sanming City,Sanming 365000,China)

机构地区：[1]福建三明市沙县总医院,福建三明365000

出　　处：《中国医药指南》2021年第11期68-69,共2页Guide of China Medicine

摘　　要：目的结合临床实践,总结出小儿鹅口疮最佳临床治疗计划。方法随机从口腔科2014年至2017年治疗的小儿鹅口疮病案中抽取80例,以选入组别的顺序分为两个小组,单数为对照组,偶数为观察组,其中对照组选取氟康唑、碳酸氢钠两种药物进行治疗;观察组选取氟康唑、制霉菌素+碳酸氢钠进行联合治疗,对两组患儿病情改善情况进行对比分析。结果观察组1~2 d内白斑消失情况、临床总有效率均优于对照组,且不良反应发生率及复发率更低(P<0.05)。结论对于小儿鹅口疮,氟康唑、制霉菌素+碳酸氢钠联合治疗尤为关键,值得临床广泛推广运用。Objective Combined with clinical practice,summarize the best clinical treatment plan for children with thrush.Method Randomly draw 80 cases of pediatric thrush during the period of dentistry from 2014 to 2017,and divide them into two groups in the order of selection into groups.The odd number is the control group and the even number is the observation group.The control group selected conazole and sodium bicarbonate was used for treatment;the observation group selected fluconazole,nystatin,and sodium bicarbonate for combined treatment,and compared and analyzed the improvement of the two groups.Results The leukoplakia disappeared within 1-2 days and the total clinical effective rate of the observation group were better than the control group,and the incidence of adverse reactions and recurrence rate were lower(P<0.05).Conclusion For children with thrush,fluconazole,nystatin+sodium bicarbonate combination therapy is particularly critical,and it is worthy of widespread clinical application.

关 键 词：小儿鹅口疮 氟康唑 制霉菌素 碳酸氢钠 白斑 

分 类 号：R725[医药卫生—儿科]