乙肝肝硬化腹水采用恩替卡韦联合腹水浓缩回输治疗的效果  

Therapeutic Effect of Entecavir Plus Concentrated Ascites Reinfusion in Patients With Hepatitis B Cirrhosis Ascites

作　　者：程祥 CHENG Xiang(Department of Infection,Wuxue First People's Hospital,Wuxue Hubei 435400,China)

机构地区：[1]武穴市第一人民医院感染科,湖北武穴435400

出　　处：《中国继续医学教育》2021年第17期149-151,共3页China Continuing Medical Education

摘　　要：目的分析乙肝肝硬化腹水患者采用恩替卡韦联合腹水浓缩回输治疗对减轻患者负担的效果。方法入组本院科室收治的乙肝肝硬化腹水患者共70例,随机分组,对照组的患者给予腹水浓缩回输治疗,观察组则在对照组的基础上增加恩替卡韦。比较两组HBV-DNA水平、腹围缩小的范围、体质量降低的水平、治疗前后患者肝纤维化指标。结果观察组HBV-DNA水平、腹围缩小范围、体质量降低水平、治疗后患者肝纤维化指标优于对照组(P<0.05)。结论乙肝肝硬化腹水患者采用恩替卡韦联合腹水浓缩回输治疗对减轻患者负担的效果确切,可有效缩小腹围,降低体质量和改善肝纤维化功能。Objective To analyze the effect of entecavir+ascites concentration and reinfusion on reducing the burden of patients with liver cirrhosis ascites.Methods 70 patients with ascites of hepatitis B cirrhosis admitted to our hospital were randomly divided into two groups.Patients in the control group were treated with ascites concentration and reinfusion,while those in the observation group were treated with entecavir on the basis of the control group.The level of HBV-DNA,the scope of abdominal circumference reduction,the level of weight loss and the index of liver fibrosis before and after treatment were compared between the two groups.Results The level of HBV-DNA,the scope of abdominal circumference reduction,the level of weight loss and the index of liver fibrosis in the observation group were better than those in the control group(P<0.05).Conclusion The treatment of entecavir+ascites concentration and reinfusion in patients with liver cirrhosis and ascites is effective in reducing the burden of patients,reducing abdominal circumference,weight and improving liver fibrosis function.

关 键 词：乙肝肝硬化腹水患者 恩替卡韦 腹水浓缩回输治疗 腹围 肝纤维化 肝功能 

分 类 号：R322[医药卫生—人体解剖和组织胚胎学]