QuEChERS快速前处理法测定人参、西洋参及其制品中杀线威等7种农药  

Determination of Seven Pesticide Residues in Ginseng and American Ginseng and Their Products Using QuEChERS Rapid Pretreatment Method

作　　者：王金子 王佳慧 付瑶 胡婷婷 黄炜婷 张鑫 张勋 WANG Jin-zi;WANG Jia-hui;FU Yao;HU Ting-ting;HUANG Wei-ting;ZHANG Xin;ZHANG Xun(Advanced Research Institute of State Drug Administration,Beijing 100000,China;Changchun Customs Technology Center,Changchun 130062,China)

机构地区：[1]国家药品监督管理局高级研修学院,北京100000 [2]长春海关技术中心,吉林长春130062

出　　处：《化学试剂》2021年第5期666-670,共5页Chemical Reagents

基　　金：吉林省科技发展重点项目(20180201060SF);国家质检总局科技项目(2016IK123)。

摘　　要：建立了检测人参、西洋参及其制品中杀线威、敌百虫、多菌灵、吡虫清、硫双威、丙硫克百威、除虫菊酯7种农药的液相色谱-串联质谱检测分析方法。样品经乙腈超声提取、QuEChERS法净化、滤膜过滤后用液相色谱-串联质谱法进行定性和定量分析。结果表明:7种农药的浓度在0.01~0.2 mg/L范围内呈现良好的线性关系(相关系数R^(2)>0.998),7种农药的检出限为0.01 mg/kg。分别选取生晒白参、西洋参、人参蜜片、西洋参蜜片样品,在0.01、0.02、0.2 mg/kg 3个浓度水平下进行加标回收试验,7种农药的加标回收率在80.0%~103.1%之间,相对标准偏差为4.86%~8.09%(n=6)。该前处理方法简便快捷、对目标物定性定量准确,适用于大量人参及人参制品的快速准确测定。A method for the simultaneous determination of 7 pesticide residues in Ginseng and Ginseng products by liquid chromatography-tandem mass pectrometry(LC-MS/MS) was established.After extracted by acetonitrile, the filtrate was purified by QuEChERS and analyzed by liquid chromatography-tandem mass spectrometry(LC-MS/MS).The calibration curves for 7 pesticides demonstrated good linearity in the range of 0.01~0.2 mg/L,with the correlation coefficients better than 0.998,and the quantification limits were 0.01 mg/kg.The average recoveries of 7 pesticides at the spiked levels of 0.01,0.02,0.2 mg/kg ranged from 80.0%~103.1% with RSDs of 4.86%~8.09%(n=6).It had been proved that the new method with many advantages such as simplicity in operation, economical and rapid clean-up procedure.The method is suitable for rapid and accurate determination of Ginseng and American ginseng and their products.

关 键 词：人参 西洋参 QUECHERS 农药 液相色谱-串联质谱法 

分 类 号：O657.63[理学—分析化学]