神经梅毒致麻痹性痴呆3例  

Paralytic dementia caused by neurosyphilis in 3 cases

作　　者：易勤 刘超群 黄亮 YI Qin;LIU Chaoqun;HUANG Liang(Department of Pharmacy,Zhuzhou Central Hospital,Zhuzhou,Hunan 412000,China;Department of Neurology,Zhuzhou Central Hospital,Zhuzhou,Hunan 412000,China)

机构地区：[1]株洲市中心医院药学部,湖南株洲412000 [2]株洲市中心医院神经内科,湖南株洲412000

出　　处：《安徽医药》2021年第6期1177-1179,共3页Anhui Medical and Pharmaceutical Journal

摘　　要：目的总结3例由神经梅毒导致的麻痹性痴呆病人的诊治过程,积累该类病人的临床诊疗经验。方法回顾性分析2018年7月至2019年7月入住株洲市中心医院的神经梅毒所致的麻痹性痴呆病人3例的临床资料,探讨其临床表现和治疗手段。结果3例临床表现为精神行为异常的麻痹性痴呆病人,在分别给予青霉素钠320万U,每8小时1次,同时予以恩替卡韦片0.5 mg每天1次;苄星青霉素240万U,每周1次及头孢曲松2 g每天1次的抗病毒治疗后,临床症状皆有所改善。结论加强临床医务人员对麻痹性痴呆的临床表现多样化的认识,及早鉴别诊断并治疗,对麻痹性痴呆病人的预后有重要的临床意义。Objective To summarize the diagnosis and treatment process of 3 cases of paralytic dementia caused by neurosyphilis,and to accumulate the clinical diagnosis and treatment experience of such patients.Methods Three cases of paralytic dementia caused by neurosyphilis admitted to Zhuzhou Central Hospital from July 2018 to July 2019 were retrospectively analyzed,and their clinical manifestations and treatment methods were discussed.Results The treatment three patients with paralytic dementia with abnormal mental behavior were given 3.2 million U of penicillin sodium(once every 8 hours),0.5 mg of entecavir tablets(once a day),and antiviral treatment for 2.4 million U of benzylpenicillin(once a week)combined with 2 g of ceftriaxone(once a day),the clinical symptoms have improved.Conclusion It is possible to strengthen the understanding of the clinical manifestations of paralytic dementia among the medical staff and make early differential diagnosis and treatment,which is of great clinical significance for the prognosis of patients with paralytic dementia.

关 键 词：神经梅毒 痴呆 青霉素G 精神异常 

分 类 号：R759.13[医药卫生—皮肤病学与性病学] R749.1[医药卫生—临床医学]