内置可吸收肌腱连接器修复肌腱的生物力学研究  

Bio-mechanical study of tendon repair with internal absorbable tendon connector

作　　者：章鸿 张平[2] 李进[3] Zhang Hong;Zhang Ping;Li Jin(Department of Orthopaedics,the Affiliated Suzhou Hospital of Nanjing Medical University,Suzhou 215000,China;Center for Research on Biomaterials and Engineering,National Key Laboratory of Material Composites,Wuhan University of Technology,Wuhan 430070,China;Department of Hand Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China)

机构地区：[1]南京医科大学姑苏学院骨科,南京医科大学附属苏州医院骨科,215000 [2]武汉理工大学材料复合国家重点实验室生物材料与工程研究中心,430070 [3]华中科技大学同济医学院附属协和医院手外科,武汉430022

出　　处：《中华实验外科杂志》2021年第5期882-885,共4页Chinese Journal of Experimental Surgery

摘　　要：目的通过离体猪后足屈肌腱修复模型评估一种新型内置式肌腱连接器修复肌腱效果。方法用猪后足趾深屈肌腱模型,对于同一猪后足的第2、3趾分别采用内置可吸收连接器(实验组)或双津下法(对照组)予以缝合,采用Instron5848微观力学实验系统记录和分析2 mm间距形成时拉力负荷、屈服点负荷、最大抗拉负荷、修复刚度。对于取材自同一猪后足的第2、3趾测试差值采用配对t检验分析。结果内置连接器法抗拉强度显著高于双津下法,其中2 mm间距形成负荷差值为(17.93±8.66)N(t=7.169,P<0.01),屈服点负荷差值为(12.73±6.66)N(t=6.148,P<0.01),最大抗拉负荷差值为(22.06±12.43)N,差异均有统计学意义(t=6.622,P<0.01)。结论这种内置式连接器法是一种比较可靠的新型肌腱修复技术,为早期主动功能锻炼提供强有力的保障,有望减轻肌腱粘连。Objective To evaluate the efficacy of a new type of internal tendon connector in repairing tendon by porcine hindfoot flexor tendon model.Methods The deep flexor tendon of pig hind toe was used as the object of repair,and the two flexor tendons of the same pig hindfoot were sutured with internal tendon connector method or modified double Tsuge method,respectively.The tension load of 2 mm spacing,yield point load,maximum tensile load and repair stiffness were recorded and analyzed by Instron5848 micromechanics experimental system.The difference between two tendons taken from the same pig hindfoot was analyzed by paired t test.Results The tensile strength of the internal connector method was significantly greater than that of the modified double Tsuge method,in which the average load difference of 2 mm spacing,yield point and maximum tensile load were(17.93±8.66)N(t=7.169,P<0.01),(12.73±6.66)N(t=6.148,P<0.01)and(22.06±12.43)N(t=6.622,P<0.01),but there was no significant difference in tendon stiffness.Conclusion This internal tendon connector method is a new,reliable tendon repair technique,and may provide a strong guarantee for early active functional exercise,which can ameliorate the adhesion of tendon.

关 键 词：肌腱修复 生物力学 

分 类 号：R318.01[医药卫生—生物医学工程] R687.2[医药卫生—基础医学]