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作 者:边文建 巩翠华 高风华[1] 杨绪红[1] 韩美辰 BIAN Wen-jian;GONG Cui-hua;GAO Feng-hua;YANG Xu-hong;HAN Mei-chen(Zibo Center for Disease Control and Prevention,Zibo,Shandong 255026,China)
机构地区:[1]淄博市疾病预防控制中心,山东淄博255026
出 处:《现代预防医学》2021年第10期1891-1895,共5页Modern Preventive Medicine
摘 要:目的分析淄博市2007-2020年学生HIV/AIDS病例的流行特征,为制定全市学生艾滋病防控策略提供依据。方法收集艾滋病综合防治信息系统CARD数据库和FLOW数据库中现住址为淄博市、首次报告时职业为学生的所有病例信息及实验室相关检查结果。采用描述性流行病学方法,对学生病例的一般情况、感染途径、高危行为、实验室检测、样本来源等情况进行统计分析。结果共报告学生HIV/AIDS病例53例,其中HIV 42例(79.2%),AIDS 11例(20.8%),男性52例(98.1%),平均发病年龄(20.64±3.08)岁,大专及以上文化程度43例(81.1%)。学生病例数总体呈逐年上升趋势(F=93.984,P<0.001)。感染途径以男男同性性传播为主(92.5%),病例来源以咨询检测为主(52.8%)。53例病例均进行了首次CD4^(+)T淋巴细胞检测,晚发现率7.5%。不同年份(P=0.014)、年龄(χ^(2)=4.627,P=0.031)、病例来源(χ^(2)=4.567,P=0.033)的首次CD4^(+)T淋巴细胞计数高低(有无免疫缺陷)差异有统计学意义,末次CD4^(+)T淋巴细胞检测值与首次检查值差异无统计学意义(t=0.857,P=0.395)。结论淄博市学生HIV/AIDS病例数逐年增加,以大专及以上、男男同性性传播为主,应将男男性行为人群作为学生艾滋病防控工作的重点人群;校园健康教育对于预防控制学生青少年艾滋病以及病例的早发现、早干预、早治疗至关重要。Objective To analyze the epidemiological characteristics of HIV/AIDS cases among students in Zibo city from 2007 to 2020,and to provide a basis for the development of a city-wide student AIDS prevention and control strategy.Methods Information on all cases with current address in Zibo city and occupation as students at the time of first report and laboratory related test results were collected from the comprehensive AIDS reporting database(CARD)and FLOW database.Descriptive epidemiological methods were used to statistically analyze the general conditions,routes of infection,high-risk behaviors,laboratory tests,and sample sources of student cases.Results A total of 53 student HIV/AIDS cases were reported,including 42 cases of HIV(79.2%)and 11 cases of AIDS(20.8%),52 cases of males(98.1%),with an average age of onset of(20.64±3.08)years and 43 cases with college education or above(81.1%).The overall number of student cases showed an increasing trend year by year(F=93.984,P<0.001).The route of infection was predominantly male-to-male sexual transmission(92.5%),and the source of cases was mainly counseling tests(52.8%).All 53 cases underwent first CD4^(+)Tlymphocyte testing,with a late detection rate of 7.5%.There were statistically significant differences in high and low first CD4^(+)T lymphocyte counts(with and without immunodeficiency)according to year(P=0.014),age(χ^(2)=4.627,P=0.031),and case source(χ^(2)=4.567,P=0.033),and no statistically significant differences between the last CD4^(+)T lymphocyte test values and the first test values(t=0.857,P=0.395).Conclusion The number of HIV/AIDS cases among students in Zibo city is increasing year by year,with college and above,male-to-male sexual transmission.Men who have sex with men should be considered as the key population for student AIDS prevention and control.Campus health education is crucial for the prevention and control of AIDS among student adolescents as well as early detection,intervention and treatment of cases.
关 键 词:获得性免疫缺陷综合症 学生 流行特征 性行为
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