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作 者:陈燕 申化英 王善容 高洪波[2] CHEN Yan;SHEN Huaying;WANG Shanrong;GAO Hongbo(The Maternal and Child Care Service Centre of Dazhu County,Dazhu 635199,Sichuan Province,China;People's Hospital of Dazhu County,Dazhu 635199,Sichuan Province,China)
机构地区:[1]大竹县妇幼保健院,四川大竹635199 [2]大竹县人民医院,四川大竹635199
出 处:《预防医学情报杂志》2021年第5期657-661,共5页Journal of Preventive Medicine Information
摘 要:目的分析大竹县预防艾滋病母婴传播工作开展情况及其效果,为今后工作的开展提供参考依据。方法收集大竹县2008-01/2018-12确认感染的HIV阳性孕产妇的母婴阻断相关资料,对其感染情况、妊娠及分娩情况、用药情况、新生儿用药及感染情况等进行分析。采用SPSS 22.0软件进行χ2检验、χ2趋势检验。结果 2008-2018年,大竹县孕产妇的HIV抗体检测率为89.72%,阳性率为1.08‰;共检出81例HIV阳性孕产妇,平均年龄为(30.77±6.68)岁,59.26%为家务及待业者,59.26%为初中文化程度;有新生儿出生的52例HIV阳性孕产妇的用药率为73.08%,新生儿用药率为96.23%;51名儿童在18月龄进行了HIV抗体检测,无1例阳性,经死亡校正后母婴传播率为0.87%。结论通过开展孕产妇艾滋病咨询与检测,及时、合理、正确地应用抗病毒药物,采取产科干预等综合措施,能够降低艾滋病的母婴传播率。Objective To analysis the situation and effectiveness of the prevention of mother-to-child HIV transmission in Dazhu county,and to provide the basis for the further prevention and control.Methods The data of HIV examination, infection status, clinical medication of HIV-positive pregnant women and their infants from Jan 2008 to Dec 2018 were analyzed. chi-square test and trend chi-square test were used by SPSS 22.0 software. Results The detection rate of HIV antibody in pregnant women from 2008 to 2018 was 89.72%. And 1.08‰ of pregnant women were diagnosed with HIV-positive. The mean age of 81 cases of HIV-positive pregnant women was(30.77±6.68),and 59.26% of them were unemployed and 59.26% of them had the educational level of junior high school. The rate of HIV-positive pregnant women who took anti-HIV drugs was73.08%,while the rate of their infants was 96.23%. 51 infants had been tested HIV antibody at the end of the 18 th month,no one was diagnosed to be positive. And the mother-to-child transmission rate of HIV was 0.87%. Conclusion By carrying out AIDS counseling and teasting for pregnant women, and applying antiviral drugs in timely, reasonable and correctly,comprehensive prevention of mother-to-child transmission given to HIV-positive pregnant women and their infants can effectively reduce the incidence of HIV in children.
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