Dual Fluorescent Protein(yEGFP/DsRed-Express-2) Bioassay System for Rapid Screening for Chemical Mutagens Based on RNR3 Regulation in Saccharomyces Cerevisiae  

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作  者:LIU Xing CHEN Geng LU Gang Yu YAO Jia ZHU Fang Yu XU Jun LI Xiang Ming 

机构地区:[1]Preventive Medicine Department of Yangzhou Medical College,Yangzhou University,Yangzhou 225001,Jiangsu,China [2]Institute of Translational Medicine,Medical College,Yangzhou University,Yangzhou 225001,Jiangsu,China [3]Institute of Toxicology and Risk Assessment,Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 210009,Jiangsu,China [4]Jiangsu Key Laboratory of Experimental and Translational Non-coding RNA Research,Yangzhou 225001,Jiangsu,China

出  处:《Biomedical and Environmental Sciences》2021年第5期421-424,共4页生物医学与环境科学(英文版)

摘  要:Over the past several years,the most widely used in vitro tests for mutagenicity have been those performed on bacteria.These include the Ames test,SOS,and SOS/umu chromotest[1,2].The Ames test is the most commonly used system,but it is not automatable and requires several strains to detect different types of mutagens.

关 键 词:SOS/UMU AUTOMATA AMES 

分 类 号:Q93-33[生物学—微生物学]

 

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