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作 者:周丽 ZHOU Li(Laboratory Department,Xianning Hospital of Traditional Chinese Medicine,Xianning Hubei 437000,China)
机构地区:[1]湖北省咸宁市中医医院检验科,湖北咸宁437000
出 处:《中国继续医学教育》2021年第18期133-136,共4页China Continuing Medical Education
摘 要:目的探讨危重感染患者降钙素原(PCT)水平变化及对预后的预测价值。方法回顾性分析2017年1—12月医院收治的128例危重症患者的临床资料,比较感染组和非感染组一般资料及PCT、D-二聚体(DD)水平变化,比较死亡组和存活组PCT、DD水平,评估PCT、DD在危重感染患者预后中的预测价值。结果感染组PCT、DD明显高于非感染组(P<0.05),死亡组PCT、DD明显高于存活组,差异有统计学意义(P<0.05);PCT在评估危重感染预后中的ROC曲线下面积为0.994,灵敏度为0.936,DD的曲线下面积为0.880,灵敏度为0.916。结论PCT可作为危重感染患者预后评估的有效指标。Objective To investigate changes of procalcitonin(PCT)levels in critical infection patients and the predictive value for prognosis.Methods The clinical data of 128 critically ill patients who were admitted to the hospital from January to December 2017 were retrospectively analyzed.The general data,changes in PCT and D-dimer(DD)level were compared between infection group and non-infection group.PCT,and DD levels were compared between death group and survival group.The predictive value of PCT and DD for prognosis of critical infection patients was evaluated.Results PCT and DD in infection group were significantly higher than those in non-infection group(P<0.05).PCT,and DD in death group were significantly higher than those in survival group(P<0.05).The area under ROC curve and sensitivity of PCT in evaluating prognosis of critical infection were 0.994 and 0.936,respectively.The area under ROC curve of DD was 0.880,the sensitivity was 0.916.Conclusion PCT can be used as an effective index for prognosis assessment of critical infection patients.
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