中文版输尿管支架症状问卷的译制及信度、效度的初步验证  

Validation of the Chinese version of ureteral stent symptom questionnaire

作　　者：马凯[1] 曲星珂[1] 许清泉[1] 熊六林[1] 叶雄俊[1] 安立哲 陈伟男[1] 黄晓波[1] Ma Kai;Qu Xingke;Xu Qingquan;Xiong Liulin;Ye Xiongjun;An Lizhe;Chen Weinan;Huang Xiaobo(Urology and Lithotripsy Center,Peking University People′s Hospital,Beijing 100034,China)

机构地区：[1]北京大学人民医院泌尿与碎石中心,100034

出　　处：《中华全科医师杂志》2021年第5期587-593,共7页Chinese Journal of General Practitioners

摘　　要：目的开发中文版的输尿管支架症状问卷(USSQ)并进行信度和效度验证。方法采用多步骤的翻译方法将英文版USSQ翻译为中文USSQ。采用中文USSQ及欧洲五维健康量表可视模拟比例尺(EQ-VAS)、国际前列腺症状评分(IPSS)表(男性患者)及泌尿生殖道症状调查表(UDI-6)(女性患者),对连续纳入的83例术后留置单侧输尿管支架管的患者(试验组)和90例健康志愿者(对照组)在术后第1、4和8周(分别为术后留置单侧输尿管支架管后、拔除输尿管支架管时、拔出输尿管支架管后4周时)行问卷调查,采用克朗巴赫α系数评价问卷内部一致性、斯皮尔曼相关系数评价重测信度,以斯皮尔曼相关系数检验同证效度,以秩和检验评价改变的敏感度和区分效度。结果中文USSQ与英文版USSQ相同,共有6个维度、43个问题。试验组78例患者(男/女为45/33例)、对照组90例患者(男/女为41/49例)完成问卷,问卷的克朗巴赫α系数为0.60~0.78,斯皮尔曼相关系数为0.69~0.91;6个维度之间的15项比较中,11项斯皮尔曼相关系数为0.31~0.50。试验组男性患者术后第4周的尿路症状评分与IPSS评分之间的斯皮尔曼相关系数>0.60,女性患者术后第4周的尿路症状评分与UDI-6之间的斯皮尔曼相关系数为0.522,改变的敏感性和区分效度在尿路症状、躯体疼痛、总体健康情况、工作表现、其他问题维度中也显示了很好的结果(均P<0.01);因试验组术后第1、4、8周分别有1(1.3%)、6(7.7%)、34(43.6%)例患者有性生活,故未对问卷的性生活维度进行分析。结论中文版USSQ在中国人群中具有较好的信度和效度,可以用于评估留置输尿管支架管对患者生命质量的影响。Objectives To validate the Chinese version of the Ureteral Stent Symptoms Questionnaire(Chinese-USSQ)in patients with an indwelling ureteral stent.Methods The original USSQ was translated into Chinese and linguistically validated following the cross-cultural adaptation of health-related quality of life measures.A total of 83 patients(cases)with indwelling ureteral stent and 90 healthy subjects(controls)were asked to complete the Chinese-USSQ as well as European Quality of Life Visual Analogue scale(EQ-VAS)(for both genders),the International Prostate Symptom Scale(IPSS)(for male),and Urogenital Distress Inventory-6(for female).Patients were evaluated at weeks 1 and 4 after stent placement and at week 4 after removal.The psychometric properties of the questionnaire were analyzed.Results The Chinese version of USSQ include 43 items,which addressed various domains of health(6 sections)covering urinary symptoms,pain,general health,work performance and sexual matters with additional problems.A total of 78 patients(45 males and 33 females)and 90 controls(41 males and 49 females)were included for analysis.Internal consistencies(Cronbach′sαcoefficients:0.60-0.78)and test-retest reliability(Spearman correlation coefficient:0.69-0.91)were satisfactory for urinary symptom,body pain,general health,and work performance domains.Most USSQ domains showed moderate correlations with each other.The convergent validity determined by correlation between other instruments and corresponding USSQ domain was satisfactory.At week 4 it was moderate for the urinary symptoms index compared to the IPSS in men(Spearman correlation coefficient>0.60),for the urinalry symptoms index compared to the UDI-6 score in women(Spearman correlation coefficient 0.52).Sensitivity to change and discriminant validity were also good in most domains(P<0.01).Only a small proportion of the study population had an active sexual life with the stent in situ,which limited its analysis.Only 1(1.3%)and 6(7.7%)patients had an active sex life at week 1 and 4 after ste

关 键 词：支架 输尿管 问卷 生活质量 信度 效度 

分 类 号：R699.4[医药卫生—泌尿科学]