鼠疫疫苗研究进展  

Progress in plague vaccine research

作　　者：匡衡 蔡欣(综述) 汪茂荣(审校) KUANG Heng;CAI Xin;WANG Mao-rong(Anhui Medical University Affiliated with Bayi Clinical College,Nanjing 210002,Jiangsu,China;Institute of Liver Disease,General Hospital of Eastern Theater Command,PLA,Nanjing 210002,Jiangsu,China)

机构地区：[1]安徽医科大学八一临床学院,南京210002 [2]东部战区总医院秦淮医疗区肝病科,南京210002

出　　处：《东南国防医药》2021年第3期307-310,共4页Military Medical Journal of Southeast China

摘　　要：鼠疫主要依赖抗生素治疗,近年来随着耐药鼠疫杆菌的发现及流行,鼠疫疫苗的应用逐渐增多。目前国内使用的鼠疫疫苗主要为减毒活疫苗,而亚单位疫苗、结合疫苗和DNA疫苗仍在研发中,文章主要就近年来鼠疫疫苗的研究方向,研究突破和对未来鼠疫疫苗应用的展望进行综述。Plague is mainly handled by antibiotics.With the discovery and prevalence of drug-resistant Yersinia pestis in recent years,the application of plague vaccine is increasing gradually.Presently,the plague vaccine used in China is mainly live attenuated vaccine,while the subunit vaccine,conjugate vaccine and DNA vaccine are still under development.In this paper,the research direction of plague vaccine in recent years,the research breakthrough and the prospect of future application of plague vaccine is summarized.

关 键 词：鼠疫 疫苗 研究进展 

分 类 号：R516.8[医药卫生—内科学]