孕妇尿碘在100~149μg/L时对其甲状腺功能及子代的影响  

The effect of pregnant women's urinary iodine at 100-149μg/L on thyroid function and offspring

作　　者：何礼丹 陈志辉[1,2] He Lidan;Chen Zhihui(Department of Endemic Disease,Center for Disease Control and Prevention of Fujian Province,Fuzhou 350001,China;School of Public Health,Fujian Medical University,Fuzhou 350004,China)

机构地区：[1]福建省疾病预防控制中心地病室,福州350001 [2]福建医科大学公共卫生学院,福州350004

出　　处：《中华地方病学杂志》2021年第5期426-430,共5页Chinese Journal of Endemiology

基　　金：福建省科技创新平台建设项目(2019Y2001);福建省自然科学基金面上项目(2020J01093)。

摘　　要：碘元素是胎儿生长发育必不可少的微量元素,当前越来越多的调查显示孕妇尿碘水平位于100~149μg/L,该尿碘范围值低于世界卫生组织(WHO)建议的水平。在此碘营养水平下,不同的调查显示对孕妇的甲状腺功能有不同的影响,而对胎儿的生长发育将产生何种影响,需要进行长远客观的评价,目前从发育、智商和心理行为3个方面进行全面评价的研究尚不多。本文通过梳理相关已发表的研究,为进一步明确孕期碘营养水平对孕妇甲状腺功能及其后代生长发育的影响提供参考。Iodine is an essential trace element for growth and development of fetus.More and more surveys currently show that the urinary iodine level of pregnant women is between 100-149μg/L,which is lower than the level recommended by the World Health Organization(WHO).Under this level of iodine nutrition,different investigations have shown different effects on thyroid function of pregnant women,and the impact on growth and development of the fetus requires long-term objective evaluation.At present,there are three aspects:development,intelligence quotient(IQ),and psychological behavior.There are not many studies on comprehensive evaluation.This article combs the related published research to provide a reference for further clarifying the influence of iodine nutrition level during pregnancy on thyroid function of pregnant women and the growth and development of their offspring.

关 键 词：孕妇 碘缺乏 子代生长发育 甲状腺功能 

分 类 号：R715.3[医药卫生—妇产科学]