腹膜透析在急性出血坏死性胰腺炎治疗中的应用价值  

Application Value of Peritoneal Dialysis in the Treatment of Acute Hemorrhagic Necrotizing Pancreatitis

作　　者：路华 LU Hua(Department of General,the Third Affiliated Hospital of Guizhou Medical University,Duyun,Guizhou Province,558000 China)

机构地区：[1]贵州医科大学第三附属医院综合科,贵州都匀558000

出　　处：《中外医疗》2021年第12期34-36,共3页China & Foreign Medical Treatment

摘　　要：目的对急性出血坏死性胰腺炎患者采取腹膜透析治疗,并分析其应用价值。方法方便选取2018年1月—2020年1月,在该院治疗的82例急性出血坏死性胰腺炎患者,将其分为两组。对照组41例,接受CRRT治疗;观察组41例,接受腹膜透析治疗。对比两组患者症状缓解、相关指标恢复时间以及APACHEⅡ评分、Balthazar CT积分、炎症因子等。结果观察组患者的腹痛、腹胀症状缓解时间(56.46±14.46)、(98.79±21.45)h和血、尿淀粉酶恢复时间(7.18±0.95)、(8.38±0.71)d均明显短于对照组,差异有统计学意义(t=11.556、10.478、6.882、7.588,P<0.05);治疗后3 d,观察组患者的APACHEⅡ评分(6.94±0.58)分、Balthazar CT积分(5.65±0.54)分以及IL-6(62.12±5.45)pg/mL、TNF-α(21.56±3.79)ng/L、CRP水平(47.78±5.85)mg/L等炎症因子水平均明显低于对照组,差异有统计学意义(t=4.408、5.374、8.528、4.398、5.722,P<0.05)。结论对急性出血坏死性胰腺炎患者采取腹膜透析治疗可缩短病情缓解时间,提高治疗效果,促进炎性反应消退,值得推广。Objective To take peritoneal dialysis treatment for patients with acute hemorrhagic necrotizing pancreatitis and analyze its application value.Methods From January 2018 to January 2020,82 patients with acute hemorrhagic necrotizing pancreatitis treated in the hospital were conveniently selected and divided into two groups.41 cases in the control group received CRRT treatment;41 cases in the observation group received peritoneal dialysis treatment.The symptom relief,recovery time of related indicators,APACHEⅡscore,Balthazar CT score,and inflammatory factors were compared between the two groups.Results The relief time of abdominal pain and bloating symptoms of the observation group(56.46±14.46)h,(98.79±21.45)h and the recovery time of blood and urine amylase(7.18±0.95)d,(8.38±0.71)d were significantly shorter than those of the control group,the difference was statistically significant(t=11.556,10.478,6.882,7.588,P<0.05);3 d after treatment,the observation group had APACHEⅡscore(6.94±0.58)points,Balthazar CT score(5.65±0.54)points,and IL-6(62.12±5.45)pg/mL,TNF-α(21.56±3.79)ng/L,CRP level(47.78±5.85)mg/L and other inflammatory factors were significantly lower than the control group,the difference was statistically significant(t=4.408,5.374,8.528,4.398,5.722,P<0.05).Conclusion Peritoneal dialysis treatment for patients with acute hemorrhagic necrotizing pancreatitis can shorten the remission time,improve the treatment effect,and promote the resolution of inflammatory response,which is worthy of promotion.

关 键 词：急性 坏死性 胰腺炎 腹膜透析 

分 类 号：R657.5[医药卫生—外科学]