人工喂养、母乳喂养以及辅食介入时机与婴幼儿过敏性疾病的关系研究  

Study on relationships of artificial feeding, breastfeeding and complementary food intervention timing with infantile allergic diseases

作　　者：黄维勇[1] 朱然科[1] 宁静 吴婕翎[1] HUANG Weiyong;ZHU Ranke;NING Jing;WU Jieling(Department of Child Health,Guangdong Provincial Maternity and Child Health Hospital,Guangdong Guangzhou 511400,China)

机构地区：[1]广东省妇幼保健院儿童保健科,广东广州511400

出　　处：《中国妇幼健康研究》2021年第5期668-672,共5页Chinese Journal of Woman and Child Health Research

基　　金：广东省医学科学技术研究基金(A2018156)。

摘　　要：目的探讨人工喂养、母乳喂养以及辅食介入时机与婴幼儿过敏性疾病的关系。方法选取2019年6月至2020年10月于广东省妇幼保健院接受过敏性疾病诊断的243例婴幼儿为研究对象,其中人工喂养儿86例(人工喂养组)、母乳喂养儿157例(母乳喂养组),分析人工喂养、母乳喂养的喂养时间及婴幼儿辅食介入时机与过敏性疾病的关系。结果人工喂养组、母乳喂养组中喂养时间<3个月的婴幼儿过敏发生率对比差异无统计学意义(P>0.05);母乳喂养组中喂养时间为3~6个月的婴幼儿、>6个月的婴幼儿过敏发生率均低于人工喂养组,差异有统计学意义(χ^(2)值分别为4.157、5.597,均P<0.05);母乳持续喂养3~6个月的婴幼儿在6月龄前介入鸡蛋辅食的过敏发生率高于6月龄以后的过敏发生率,差异有统计学意义(36.36%vs.9.38%,χ^(2)=4.309,P<0.05);人工持续喂养3~6月的婴幼儿在6月龄前介入鸡蛋辅食的过敏发生率也高于6月龄以后的过敏发生率,差异有统计学意义(66.67%vs.23.53%,χ^(2)=5.396,P<0.05)。结论母乳喂养且喂养持续时间大于3个月可明显减少过敏性疾病的发生,辅食在6月龄以后介入较佳。Objective To explore relationships of artificial feeding, breastfeeding, and complementary food intervention timing with infantile allergic diseases.Methods 243 infants and young children who were diagnozed as allergic diseases at Guangdong Provincial Maternity and Child Health Hospital over a period from June 2019 to October 2020 were selected as research subjects, including 86 artificially fed infants(in artificial feeding group) and 157 breastfed infants(in breastfeeding group).The relationships of artificial feeding, time of breastfeeding and timing of infant complementary food intervention with infantile allergic diseases were analyzed.Results For the infants and young children whose continuous feeding time was less than 3 months, there was no statistically significant difference in incidence of allergies between the artificial feeding group and the breastfeeding group(P>0.05).The incidence of allergies in these infants and young children who were fed for 3~6 months and >6 months of continuous breastfeeding in the breastfeeding group was lower than that in the artificial feeding group at same time points, and the differences were statistically significant(χ^(2)=4.157 and 5.597 respectively, both P<0.05).The incidence of allergies in those infants and young children who were continuously breastfed for 3~6 months and were intervened with egg supplements before 6 months of age was higher than that in the infants and young children who were intervened with egg supplements after 6 months of age, and the difference was statistically significant(36.36% vs.9.38%,χ^(2)=4.309,P<0.05).The incidence of allergies in the infants and young children who were given continuous artificial feeding for 3~6 months and were intervened with egg supplements before 6 months of age was higher than that in those infants and young children who were intervened with egg supplements after 6 months of age, and the difference was statistically significant(66.67% vs.23.53%,χ^(2)=5.396,P<0.05).Conclusion Breastfeeding and continuous breastf

关 键 词：喂养方式 辅食介入时机 婴幼儿 过敏性疾病 

分 类 号：R174.4[医药卫生—妇幼卫生保健] R725.9[医药卫生—公共卫生与预防医学]