绿激光前列腺汽化术在口服抗凝药物前列腺增生患者中的应用  

Application of Green Laser Prostate Vaporization in Patients with Benign Prostatic Hyperplasia with Oral Anticoagulant Drugs

作　　者：孟祥锋[1] MENG Xiangfeng(Department of Urology,Zoucheng People's Hospital,Jining,Shandong Province,273500 China)

机构地区：[1]邹城市人民医院泌尿外科,山东济宁273500

出　　处：《世界复合医学》2021年第4期4-7,共4页World Journal of Complex Medicine

摘　　要：目的探究绿激光前列腺汽化术在口服抗凝药物前列腺增生患者中的应用价值。方法 2019年2月—2020年2月,随机抽取该院收治的116例前列腺增生患者展开相关研究,并根据患者围术期是否口服抗凝药物将患者分为试验组(围术期口服抗凝药物继续治疗)、对照组(术前1周停止口服抗凝药物治疗),每组58例,两组患者均进行绿激光前列腺汽化术治疗疾病,比较两组患者的临床疗效。结果试验组的手术操作时间(45.35±8.33)min、术中激光耗能(185.33±60.27)kJ、术中出血量(32.11±6.87)mL、术中灌注量(12.76±4.35)L、平均住院天数(3.87±0.53)d与对照组(45.98±8.52)min、(186.11±60.85)kJ、(31.56±6.45)mL、(13.02±4.41)L、(3.90±0.54)d比较,差异无统计学意义(t=0.403,P=0.688;t=0.069,P=0.945;t=0.444,P=0.658;t=0.320,P=0.750;t=0.302,P=0.763);试验组的术后保留导尿时间(3.11±0.45)d、术后膀胱冲洗时间(23.76±6.53)d与对照组(2.53±0.47)d、(14.03±3.56)d比较,差异有统计学意义(t=6.788、9.963,P<0.001)。试验组的手术前的IPSS评分(28.32±3.41)分、QOL评分(5.59±0.98)分、最大尿流率(6.21±1.58)mL/s、剩余尿量(79.08±23.22)m L与对照组(28.40±3.44)分、(5.67±0.96)分、(6.34±1.63)mL/s、(79.54±28.57)mL比较,差异无统计学意义(t=0.126,P=0.900;t=0.444,P=0.658;t=0.436,P=0.664;t=0.095,P=0.924);两组患者手术后的IPSS评分、QOL评分、最大尿流率、剩余尿量均优于手术前,但试验组的手术后的IPSS评分(6.65±1.76)分、QOL评分(1.53±0.67)分、最大尿流率(20.09±3.45)mL/s、剩余尿量(30.27±13.25)mL与对照组(6.80±1.83)分、(1.60±0.70)分、(20.45±3.60)mL/s、(30.01±13.40)mL比较,差异无统计学意义(t=0.450,P=0.654;t=0.550,P=0.583;t=0.550,P=0.583;t=0.105,P=0.917)。结论绿激光前列腺汽化术在口服抗凝药物前列腺增生患者的治疗中,具有显著效果。患者的手术指标、膀胱功能有保障。Objective To explore and observe the application value of green laser prostate vaporization in patients with benign prostatic hyperplasia with oral anticoagulant drugs.Methods From February 2019 to February 2020,116 patients with benign prostatic hyperplasia admitted to the hospital were randomly selected to carry out related research,and the patients were divided into test group(oral anticoagulants continue treatment with coagulation drugs during the perioperative period)and the control group(stop oral anticoagulation treatment 1 week before surgery)according to whether the patients took anticoagulant drugs during the perioperative period,each group had 58 patients,and both groups have undergone green laser vaporization of the prostate to treat the disease.Compared the clinical efficacy of the two groups of patients.Results The operation time of the test group was(45.35±8.33)min,the laser energy consumption(185.33±60.27)kJ,the blood loss(32.11±6.87)mL,the intraoperative perfusion(12.76±4.35)L,average number of days of hospitalization(3.87±0.53)d compared with the control group(45.98±8.52)min,(186.11±60.85)kJ,(31.56±6.45)mL,(13.02±4.41)L,(3.90±0.54)d,the difference was not statistically significant(t=0.403,P=0.688;t=0.069,P=0.945;t=0.444,P=0.658;t=0.320,P=0.750;t=0.302,P=0.763);postoperative retention urine time of the test group(3.11±0.45)d,postoperative bladder irrigation time(23.76±6.53)d compared with the control group(2.53±0.47)d,(14.03±3.56)d,the difference was statistically significant(t=6.788,9.963,P<0.001).The preoperative IPSS score(28.32±3.41)points,QOL score(5.59±0.98)points,maximum urine flow rate(6.21±1.58)mL/s,remaining urine volume(79.08±23.22)mL and the control group(28.40±3.44)points,(5.67±0.96)points,(6.34±1.63)mL/s,(79.54±28.57)mL,the difference was not statistically significant(t=0.126,P=0.900;t=0.444,P=0.658;t=0.436,P=0.664;t=0.095,P=0.924);the comparison of IPSS score,QOL score,maximum urine flow rate,and remaining urine volume after surgery in the two groups were bett

关 键 词：前列腺增生 抗凝药物 绿激光前列腺汽化术 IPSS评分 QOL评分 最大尿流率 剩余尿量 

分 类 号：R4[医药卫生—临床医学]