脓毒症与急性肾损伤  

Sepsis and acute kidney injury

作　　者：李一鸣[1] 祝媛 张婧[1] 徐冬雪 柳叶 刘芳[1] 彭志勇[1] Li Yiming;Zhu Yuan;Zhang Jing;Xu Dongxue;Liu Ye;Liu Fang;Peng Zhiyong(Department of Critical Care Medicine,Zhongnan Hospital of Wuhan University,Wuhan 430071,China)

机构地区：[1]武汉大学中南医院重症医学科,武汉430071

出　　处：《中华医学杂志》2021年第17期1210-1213,共4页National Medical Journal of China

基　　金：国家自然科学基金(面上项目)(81971816、81772046)。

摘　　要：脓毒症是机体对感染的反应失调而导致危及生命的器官功能障碍,肾脏是脓毒症最常累及的器官之一,脓毒症急性肾损伤发病率高、死亡率高。随着研究的不断深入,关于脓毒症急性肾损伤的早期识别、发病机制、诊疗的研究逐年增多,本文整理相关文献,从脓毒症AKI的早期诊断、病理生理、治疗方法、恢复和随访等方面进行阐述,以期提高脓毒症AKI在临床与基础方面的认识,降低脓毒症AKI的死亡率。Sepsis is a life‑threatening multiple organ dysfunction syndrome caused by infection,and kidney is one of the most organs susceptible to injury in sepsis.Critical ill patients with sepsis often suffer from acute kidney injury(AKI)of varying degrees with a high mortality.There are more and more researches on the early identification,pathogenesis,diagnosis and treatment of acute kidney injury in sepsis.In order to improve the understanding and reduce the mortality of acute kidney injury,this review briefly discussed the early identification,physio‑pathologic mechanism,treatment,prognosis and follow up.

关 键 词：脓毒症 急性肾损伤 早期诊断与治疗 恢复和随访 

分 类 号：R459.7[医药卫生—急诊医学] R692[医药卫生—治疗学]