甲强龙在重度支气管哮喘院前急救中的临床效果观察  

Clinical effect of methylprednisolone in pre-hospital emergency treatment of severe bronchial asthma

作　　者：周轶凡 ZHOU Yi-fan(Dalian Emergency Center,Dalian 116021,China)

机构地区：[1]大连市急救中心,116021

出　　处：《中国实用医药》2021年第16期113-115,共3页China Practical Medicine

摘　　要：目的研究重度支气管哮喘患者院前急救中使用注射用甲泼尼龙琥珀酸钠(商品名:甲强龙)治疗的效果。方法选取90例重度支气管哮喘急性发作患者为研究对象,救护车到达现场后,立刻对患者采取甲强龙治疗,对比患者不同时间血氧饱和度、呼吸频率、心率及临床效果。结果患者在上救护车后的呼吸频率及心率分别为(27.85±5.24)、(115.68±8.36)次/min,到达医院时的呼吸频率及心率分别为(22.18±4.32)、(100.36±5.45)次/min,均低于救治前的(31.89±7.28)、(138.12±9.85)次/min,差异具有统计学意义(P<0.05)。患者在上救护车后和到达医院时的临床疗效评分分别为(7.41±0.84)、(6.08±1.28)分,均低于救治前的(9.19±1.18)分,差异具有统计学意义(P<0.05)。患者在上救护车后和到达医院时的动脉血氧饱和度和静脉血氧饱和度均高于救治前,差异具有统计学意义(P<0.05)。结论对重度支气管哮喘患者在院前急救中采取甲强龙治疗,能够改善患者的血氧饱和度,在一定程度上缓解患者咳嗽喘息的症状,有效改善患者的呼吸频率、心率,值得推广应用。Objective To study the effect of methylprednisolone sodium succinate for injection(trade name:Solu-Medrol)in pre-hospital emergency treatment of severe bronchial asthma.Methods There were 90 patients with severe bronchial asthma as study subjects.After the ambulance arrived at the scene,they were treated with methylprednisolone immediately,and the blood oxygen saturation,respiratory rate,heart rate at different time points and clinical effects were compared.Results The respiratory rate and heart rate of the patients after getting on the ambulance were(27.85±5.24)and(115.68±8.36)times/min,respectively,and the respiratory rate and heart rate when arriving at the hospital were(22.18±4.32)and(100.36±5.45)times/min,both were lower than(31.89±7.28)and(138.12±9.85)times/min before treatment,and the difference was statistically significant(P<0.05).The clinical efficacy scores of patients after going to the ambulance and arriving at the hospital were(7.41±0.84)and(6.08±1.28)points respectively,which were lower than(9.19±1.18)points before treatment,and the difference was statistically significant(P<0.05).The arterial oxygen saturation and venous oxygen saturation of patients after going to the ambulance and arriving at the hospital were higher than those before treatment,and the difference was statistically significant(P<0.05).Conclusion Methylprednisolone can improve the blood oxygen saturation of patients with severe bronchial asthma in pre-hospital emergency,relieve the symptoms of cough and wheezing to a certain extent,and effectively improve the respiratory rate and heart rate of patients,which is worthy of promotion and application.

关 键 词：甲强龙 临床治疗效果 呼吸频率 咳嗽喘息 血氧饱和度 重度支气管哮喘 

分 类 号：R562.25[医药卫生—呼吸系统]