临床药师干预对创伤骨科Ⅰ类切口手术预防性使用抗菌药物的影响  

Effect of clinical pharmacist intervention on prophylactic application of antimicrobial agents for type Ⅰ incision surgery in traumatic orthopedics

作　　者：马慧[1] 宋爱萍[1] 岳文静[1] MA Hui;SONG Ai-ping;YUE Wen-jing(Department of Clinical Pharmacy,Bayannur Hospital of Inner Mongolia,Inner Mongolia,Bayan Nur 015000,China)

机构地区：[1]内蒙古自治区巴彦淖尔市医院临床药学科,内蒙古巴彦淖尔015000

出　　处：《中国当代医药》2021年第16期142-145,共4页China Modern Medicine

摘　　要：目的探讨临床药师干预对创伤骨科Ⅰ类切口手术预防性使用抗菌药物的影响。方法选取2017年11月~2018年10月在巴彦淖尔市医院创伤骨科行清洁手术并预防性使用抗菌药物的287例患者为对照组,选取2018年11月~2019年10月行清洁手术并预防性使用抗菌药物的336例患者为干预组。对照组的围术期预防性使用抗菌药物由医师决定,而干预组临床药师下沉至创伤骨科,对不合理用药进行干预,统计两组行Ⅰ类切口手术并围术期预防性使用抗菌药物的情况,比较两组患者抗菌药物的品种选择、用法用量合理率、用药维持时间及患者术后感染情况。结果干预组预防性使用抗菌药物的品种选择、用法用量合理率高于对照组,用药维持时间短于对照组,差异有统计学意义(P<0.05);两组的感染率比较,差异无统计学意义(P>0.05)。结论临床药师干预可有效提高Ⅰ类切口手术预防性抗菌药物的合理使用。Objective To investigate the effect of clinical pharmacist intervention on prophylactic application of antibiotics in type Ⅰ incision surgery of traumatic orthopedics. Methods A total of 287 patients who received aseptic operation and prophylactic antibiotics in the Department of Orthopedics, Bayannur City Hospital from November 2017 to October 2018 were selected as the control group, and a total of 336 patients receiving aseptic operation and prophylactic antibiotics from November 2018 to October 2019 were selected as the intervention group. The perioperative prophylactic use of antibiotics in the control group was determined by the physician, while the clinical pharmacist in the intervention group went to the Department of Orthopedics for the intervention of irrational use. The type Ⅰ incision operation and perioperative prophylactic use of antibiotics in the two groups were analyzed. The selection of antimicrobial varieties, rational rate of usage and dosage, duration of administration and postoperative infection were compared between the two groups. Results The rational rate of variety selection, usage and dosage of prophylactic antibiotics in the intervention group were higher than that in the control group, and the duration of administration was shorter than that in the control group, the differences were statistically significant(P<0.05). There was no significant difference in infection rate between the two groups(P>0.05). Conclusion Clinical pharmacist intervention can effectively improve the rational use of prophylactic antibiotics in type Ⅰ incision surgery.

关 键 词：临床药师 Ⅰ类切口手术 抗菌药物 干预 

分 类 号：R978.1[医药卫生—药品]