神经肽Y系统特征及其鱼类生理调控研究进展  

Advances in Research on the Characteristics of Neuropeptide Y System and Its Physiological Regulation of Fish

作　　者：梁晶 张炳 项骁炜 王天明 杨静文 LIANG Jing;ZHANG Bing;XIANG Xiao-wei(School of Marine Science and Technology of Zhejiang Ocean University,National Engineering Research Center of Marine Facilities Aquaculture,Zhoushan 316022,China)

机构地区：[1]浙江海洋大学海洋科学与技术学院,国家海洋设施养殖工程与技术研究中心,浙江舟山316022

出　　处：《浙江海洋大学学报（自然科学版）》2020年第5期449-457,共9页Journal of Zhejiang Ocean University：Natural Science

基　　金：国家自然科学基金(41606150)。

摘　　要：神经肽Y(NPY)在脊椎动物和无脊椎动物中分布广泛,在不同生物体中参与了摄食调控、体温调节、代谢调控、生长及发育调控和心血管收缩等广泛的生理功能的调控。目前哺乳动物中神经肽Y及其受体的研究成果相对丰富和成熟,鱼类中还有待进一步系统的研究。本文主要概述了神经肽Y及其受体的研究进展,梳理了鱼类神经肽Y的发现、结构、分布特征及介导的生理功能,综述了NPY系统参与的摄食调节、通过HPG轴和HPA轴实现的神经内分泌调节调节以及对心血管和呼吸系统的调节功能,另外还补充了无脊椎动物中神经肽Y的同源蛋白神经肽F的相关研究背景,以期为深入研究神经肽Y及其受体介导的信号通路及生理功能调控提供参考。Neuropeptide Y(NPY)is widely distributed in vertebrates and invertebrates,and is involved in the regulation of food regulation,body temperature regulation,metabolic regulation,growth and development regulation,and cardiovascular contraction in different organisms.At present,the research results of neuropep-tide and its receptors in mammals are relatively rich and mature,and related research in fish remains to be further systematically studied.This paper mainly summarizes the research progress of neuropeptide and its re-ceptors,combs the discovery,structure,distribution characteristics and physiological functions of fish neu-ropeptides,and summarizes the feeding regulation of NPY system,through HPG axis and the neuroendocrine regulation of the HPA axis and the regulation of the cardiovascular and respiratory systems,as well as the re-lated research background of the neuropeptide Y homologous protein neuropeptide F in invertebrates,in order to further study the neuropeptide Y and it provides a reference for its receptor-mediated signaling pathway and regulation of physiological functions.

关 键 词：神经肽Y 神经肽Y受体 鱼类 生理功能 

分 类 号：S917.4[农业科学—水产科学]