基于肠道微生态探源《黄帝内经》泄泻五脏论  

Discussion on the theory of treating diarrhea from five viscera in Huangdi Neijing based on intestinal microecology

作　　者：李玉丽 谭周进[1] Yu-Li Li;Zhou-Jin Tan(Hunan University of Chinese Medicine,Changsha 410208,Hunan Province,China)

机构地区：[1]湖南中医药大学,湖南省长沙市410208

出　　处：《世界华人消化杂志》2021年第11期615-620,共6页World Chinese Journal of Digestology

基　　金：国家自然科学基金面上项目,No.81874460.

摘　　要：泄泻是一种常见的消化道疾病,严重影响了患者的生活质量.随着微生态学发展,泄泻与肠道微生态失调的联系已得到广泛认可.中医经典《黄帝内经》中的泄泻相关论述涉及病因病机、临床表现与治疗诸方面,尤其是开创了从五脏论治泄泻之先河.肠道菌群是一个“被遗忘的器官”,菌群失调是泄泻发病的重要机制.《黄帝内经》泄泻五脏论体现了中医理论的整体观念,与肠道微生态失调内涵高度一致.结合共同的认知基础,本文系统整理了近5年文献库中与五脏相关肠道菌群研究的文献,从《黄帝内经》论治泄泻总概论、以及泄泻从脾、肾、肝、心、肺五脏论治的微生态机制进行分析阐述.研究发现肠道菌群的动态平衡是五脏功能协调的主要特征表现,五脏功能失调又皆能引起肠道菌群紊乱.肠道菌群研究成果将成为未来探究《黄帝内经》泄泻五脏论理论内涵的一个关键的科学支点.Diarrhea is a common digestive tract disease that seriously affects the quality of life of patients.With the development of microecology,the relationship between diarrhea and intestinal microecological disorder has been widely recognized.The elaboration of diarrhea in Huangdi Neijing involves etiology,pathogenesis,clinical manifestation,and treatment,and especially,it pioneered the theory of treating diarrhea from five viscera.Intestinal flora is a“forgotten organ”,and dysbacteriosis is an important mechanism of diarrhea.The theory of treating diarrhea from five viscera in Huangdi Neijing embodies the whole concept of TCM theory,which is highly consistent with the connotation of intestinal microecological imbalance.tThis paper systematically collected the literature on intestinal flora related to the five viscera in recent five years.The general introduction of diarrhea treatment from Huangdi Neijing and the microecological mechanism of treating diarrhea from spleen,kidney,liver,heart,and lung were analyzed and expounded.We conclude that the dynamic balance of intestinal flora is the main characteristic of the coordination of functions of the five viscera,and the dysfunction of the five viscera can lead to the disorder of intestinal flora.The research results of intestinal flora will become a key scientific fulcrum to explore the connotation of the theory of treating diarrhea from five viscera in Huangdi Neijing in the future.

关 键 词：泄泻 肠道菌群 《黄帝内经》 五脏 中医 

分 类 号：R256.34[医药卫生—中医内科学]