子宫动脉栓塞术对剖宫产术后子宫瘢痕妊娠患者卵巢功能的影响及安全性分析  

Effect and safety analysis of uterine artery embolization on ovarian function in patients with uterine scar pregnancy after cesarean section

作　　者：曾威[1] 黎藜 张莉[1] 蒋清华[2] 唐艳妮 Zeng Wei;Li Li;Zhang Li;Jiang Qinghua;Tang Yanni(Department of Gynecology,Guangxi Maternal and Child Health Hospital,Nanning 530000,Guangxi,China;Department of Radiology,Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region,Nanning 530000,China;Department of Ultrasound,Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region,Nanning 530000,China)

机构地区：[1]广西壮族自治区妇幼保健院厢竹院区妇科,广西南宁530000 [2]广西壮族自治区妇幼保健院厢竹院区放射科,广西南宁530000 [3]广西壮族自治区妇幼保健院厢竹院区超声科,广西南宁530000

出　　处：《实用妇科内分泌电子杂志》2021年第6期1-4,共4页Electronic Journal of Practical Gynecological Endocrinology

基　　金：广西壮族自治区卫生和计划生育委员会自筹经费科研课题(编号Z20180075)。

摘　　要：目的分析子宫动脉栓塞术对于剖宫产术后子宫瘢痕妊娠(CSP)患者的治疗疗效及对卵巢功能的影响和安全性。方法选取120例Ⅰ型或者Ⅱ型CSP患者,依据随机数字表法分为对照组与试验组,各60例。对照组予以甲氨蝶呤治疗,试验组予以子宫动脉栓塞术治疗,比较两组清宫时出血量、住院时间、并发症发生情况与治疗前后卵巢窦卵泡数(AFC)、卵泡刺激素(FSH)、抗缪勒管激素(AMH)、黄体生成素(LH)、FSH/LH以及雌二醇(E_(2))水平。结果试验组清宫时出血量明显少于对照组,住院时间明显短于对照组,差异具有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。试验组术后月经复潮时间为(46.35±3.62)d,明显短于对照组的(52.46±3.78)d,差异具有统计学意义(P<0.05)。两组治疗前后AFC、FSH、AMH、LH、FSH/LH以及E_(2)水平比较,差异无统计学意义(P>0.05)。结论子宫动脉栓塞术治疗剖宫产术后CSP患者疗效确切,能最大程度保留其卵巢功能,且安全性较高。Objective To analyze the effect and safety of uterine artery embolization on the ovarian function of patients with scar pregnancy(CSP)after cesarean section.Methods 120 patients with type I or type II CSP were selected and divided into control group and experimental group according to random number table method,60 cases in each group.The control group was treated with methotrexate,and the experimental group was treated with uterine artery embolization.The blood loss,hospitalization time,incidence of complications,antral follicle counting(AFC),follicle-stimulating hormone(FSH),anti-mullerian hormone(AMH),luteinizing hormone(LH),FSH/LH and estradiol(E_(2))levels between groups were compared.Results During curettage,the blood loss in the experimental group was significantly lower than that in the control group;the hospitalization time was significantly shorter than that in the control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of complications between groups(P>0.05).Before and after surgery,there were no significant between-group differences about AFC,FSH,AMH,LH,FSH/LH and E_(2) levels(P>0.05).Conclusion Uterine artery embolization is effective for treatment of CSP patients after cesarean section,which can preserve their ovarian function to the greatest extent and increase the surgical safety.

关 键 词：子宫瘢痕妊娠 子宫动脉栓塞术 剖宫产术 卵巢功能 

分 类 号：R714.22[医药卫生—妇产科学]