刺参腐皮综合征发生的分子调控机制研究进展  

Research progress on molecular regulation mechanism of skin ulcer syndrome in sea cucumber Apostichopus japonicus:a review

作　　者：李成华[1,2] LI Chenghua(State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo 315832, China;Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China)

机构地区：[1]宁波大学教育部应用海洋生物技术重点实验室,浙江宁波315832 [2]青岛海洋科学技术国家实验室海洋渔业科学与食品产出功能实验室,山东青岛266071

出　　处：《大连海洋大学学报》2021年第3期355-373,共19页Journal of Dalian Ocean University

基　　金：国家自然科学基金(32073003);浙江省2019年万人计划科技创新领军人才(2019R52016);宁波市自然科学基金(2018A610345)。

摘　　要：2003年以来,海参产业发展速度和拓展规模均达到前所未有的水平,在国内形成了继海带、对虾、扇贝、海水鱼类养殖之后“第五次”海水养殖产业浪潮。伴随着养殖规模和密度的扩大,病害问题也日益凸显,已逐渐成为海参产业健康发展的瓶颈,对生态环境和食品安全威胁巨大,其中以腐皮综合征最具代表性。本文梳理分析了刺参Apostichopus japonicus腐皮综合征的主要病原,系统阐述了刺参应对病原感染的免疫调节机制和代表性病原致病机制研究进展,总结了刺参病害的生态防治方法,并在实现刺参产业健康可持续发展、病原致病机制及环境调控疾病发生研究等方面提出了相应发展对策,以期为构建绿色健康的刺参疾病防控策略提供参考。Since 2003,the development speed and scale of the sea cucumber Apostichopus japonicus industry have reached unprecedented levels,forming the“fifth”wave of marine aquaculture industry in China after kelp,prawns,scallops,and marine fish farming.With the expansion of breeding scale and density,disease problems have become increasingly prominent,and have gradually become a bottleneck for the healthy development of sea cucumber industry,posing a huge threat to the ecological environment and food safety,among which the skin ulcer syndrome(SUS)is the most representative.The main pathogens of sea cucumber suffered from SUS,systematical immune regulation mechanism of sea cucumber against pathogen infection,the research progress of representative pathogenic mechanisms and ecological control methods of sea cucumber diseases are discussed in detail.Corresponding development countermeasures are proposed for the healthy and sustainable development of the sea cucumber industry,the pathogenic mechanism of pathogens and the research on the occurrence of environmental control diseases in order to provide reference with the construction of green and healthy sea cucumber disease prevention and control strategies.

关 键 词：刺参 腐皮综合征 灿烂弧菌 免疫调控 生态防控 

分 类 号：S917.4[农业科学—水产科学]