Listeria monocytogenes bacteremia in a centenarian and pathogen traceability:A case report  

作　　者：Zhong-Ying Zhang Xiao-Ai Zhang Qian Chen Jie-Yu Wang Yun Li Zhan-Yun Wei Zi-Chen Wang 

机构地区：[1]Department of Geriatric Medicine,Xuanwu Hospital,Capital Medical University,Beijing 100053,China [2]Beijing Center for Disease Prevention and Control,Institute for Nutrition and Food Hygiene,Beijing 100053,China [3]Research Centre for Preventive Medicine of Beijing,Beijing 100053,China

出　　处：《World Journal of Clinical Cases》2021年第18期4873-4880,共8页世界临床病例杂志

基　　金：Supported by Teaching Fund of Xuanwu Hospital,Capital Medical University,China,No.2018XWJXGG-29.

摘　　要：BACKGROUND Early diagnosis and appropriate antibiotic treatment are important to survival of Listeria monocytogenes(L.monocytogenes)bacteremia.Penicillin tends to be the most commonly used antibiotic.However,there are limited data on antibiotic use in elderly patients with serious complications.We describe the clinical presentation,antibiotic therapy,and traceability of L.monocytogenes in a centenarian with a history of eating frozen food.CASE SUMMARY A 102-year-old man suffered from high fever with chill after hematochezia.Tentative diagnoses were lower gastrointestinal hemorrhage and localized peritonitis.Meropenem and ornidazole were the empirical therapy.The patient did not respond and developed multiple system dysfunction even after teicoplanin was added to the therapy.L.monocytogenes was identified from blood cultures on day 5 of admission.The patient had a history of consuming frozen dumplings.Meropenem/ornidazole/teicoplanin were replaced with meropenem/linezolid.The patient gradually became afebrile.He received meropenem/linezolid for 10 d,and piperacillin/tazobactam was applied as step-down treatment for 2 wk with good clinical results.There was no sign of relapse during follow-up after discharge.L.monocytogenes isolates from the patient and frozen dumplings belonged to different serotypes and sequence types(STs):1/2b and ST5 from the patient and 1/2c and ST9 from the dumplings.CONCLUSION More awareness of listeriosis should be raised.Linezolid might be an option for listeriosis in elderly people with serious complications.

关 键 词：Listeria monocytogenes CENTENARIAN BACTEREMIA TRACEABILITY ANTIBIOTICS Case report 

分 类 号：R516[医药卫生—内科学]