艾灸配合针刺四缝穴对矮小症患儿血清IGF-1、甲状腺功能及PedsQL评分的影响  

Effect of moxibustion combined with acupuncture at Sifeng Point on IGF-1,thyroid function,and PedsQL score in children with dwarfism

作　　者：马欣波[1] 吴兴立 MA Xin-bo;WU Xing-li(Department of Child Health Care,Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang 712000,Shaanxi,CHINA;Department of Rehabilitation Medicine,Shangluo Central Hospital,Shangluo 726000,Shaanxi,CHINA)

机构地区：[1]陕西中医药大学第二附属医院儿童保健科,陕西咸阳712000 [2]商洛市中心医院康复医学科,陕西商洛726000

出　　处：《海南医学》2021年第11期1442-1445,共4页Hainan Medical Journal

摘　　要：目的探究艾灸配合针刺四缝穴治疗对矮小症患儿血清胰岛素样生长因子-1(IGF-1)、甲状腺功能及儿童生活质量核心通用量表(PedsQL)评分的影响。方法回顾性分析2019年6月至2020年6月陕西中医药大学第二附属医院诊治的98例矮小症患儿的临床诊治资料,根据不同治疗方法分组,其中49例行艾灸治疗者纳入对照组,49例行艾灸配合针刺四缝穴治疗者纳入研究组,两组患儿的治疗时间均为6个月。比较两组患儿治疗前后的血清IGF-1、血清游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)水平及儿童生活质量核心通用量表(PedsQL)评分情况。结果两组患儿在性别、年龄、骨龄低于实际年龄2岁以上例数等一般资料比较差异均无统计学意义(P>0.05);治疗前,两组患儿的血清IGF-1水平比较差异无统计学意义(P>0.05);治疗后,两组患儿的血清IGF-1水平明显提高,且研究组的血清IGF-1水平为(135.70±9.75)μg/L,明显高于对照组的(112.15±13.70)μg/L,差异均有统计学意义(P<0.05);治疗前,两组患儿的FT3、FT4、FT3/FT4、TSH水平比较差异均无统计学意义(P>0.05);治疗后,两组患儿的FT3、FT3/FT4水平明显上升,且研究组的FT3和FT3/FT4分别为(7.50±0.65)pmol/L、0.45±0.08,明显高于对照组的(6.20±0.63)pmol/L、0.42±0.06,差异均有统计学意义(P<0.05);但两组患儿治疗前后的FT4、TSH水平比较差异均无统计学意义(P>0.05);治疗后,对照组患儿PedsQL评分中的生理功能、情感功能、社交功能、学习功能评分明显低于研究组,差异均有统计学意义(P<0.05)。结论艾灸配合针刺四缝穴治疗矮小症可改善患儿的胰岛素样生长因子水平及甲状腺功能代谢,提高患儿家庭功能及生活质量。Objective To explore the effect of moxibustion combined with acupuncture at Sifeng Point on serum insulin-like growth factor-1(IGF-1),thyroid function,and Pediatric Quality of Life Inventory(PedsQL)score in children with dwarfism.Methods From June 2019 to June 2020,the clinical diagnosis and treatment data of 98 children with dwarfism diagnosed and treated in the Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine were analyzed retrospectively.According to different treatment methods,49 patients treated with moxibustion were included in the control group,and 49 treated with moxibustion combined with acupuncture at Sifeng Point were included in the study group.The treatment lasted 6 months.The serum levels IGF-1,free triiodothyronine(FT3),free thyroxine(FT4),thyroid stimulating hormone(TSH),and children's quality of life were compared between the two groups before and after treatment.Results Between the two groups,there was no significant difference in general data,such as sex,age,number of cases with bone age lower than the actual age for more than 2 years old(P>0.05).There was no significant difference in serum IGF-1 between the two groups before treatment(P>0.05);the serum IGF-1 level of the two groups was significantly improved after treatment,and the serum IGF-1 level of the study group was(135.70±9.75)μg/L,which was significantly higher than(112.15±13.70)μg/L of the control group(P<0.05).There was no significant difference in FT3,FT4,FT3/FT4,TSH level between the two groups before treatment(P>0.05);the FT3,FT3/FT4 level of the two groups increased significantly after treatment,and the FT3 and FT3/FT4 of the study group were(7.50±0.65)pmol/L and 0.45±0.08,which were significantly higher than(6.20±0.63)pmol/L and 0.42±0.06 of the control group(P<0.05).There was no significant difference in FT4,TSH level between the two groups before and after treatment(P>0.05).The scores of physiological function,emotional function,social function and learning function were significantly hi

关 键 词：矮小症 艾灸 针刺四缝穴 胰岛素样生长因子-1 甲状腺功能 生活质量 

分 类 号：R729[医药卫生—儿科]